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Cytomegalovirus-specific cellular immune responses reviewed.
2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers review cytomegalovirus-specific cellular immune responses in a recent issue of Human Immunology.
According to recent research from Switzerland, "A large percentage of healthy individuals (50-9%) is chronically infected with cytomegalovirus (CMV). Over the past few years, several techniques were developed in order to monitor CMV-specific T-cell responses. In addition to the identification of antigen-specific T cells with peptide-loaded MHC complexes, most of the current strategies to identify CMV-specific T cells are centered on the assessment of the functions of memory T cells including their ability to mediate effector function, to proliferate or to secrete cytokines following antigen-specific stimulation."
"The investigation of these functions has allowed the characterization of the CMV-specific T-cell responses that are present during different phases of the infection," said Alexandre Harari and colleagues at the University of Lausanne. "Furthermore, it has also been shown that the ...
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Source: HighBeam Research, Cytomegalovirus-specific cellular immune responses reviewed.