AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Monoclonal antibodies recognize idiotypic immunoglobulins of lymphoma cells.
2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Human monoclonal antibodies produced in transgenic BABK kappa,lambda mice recognize idiotypic immunoglobulins of human lymphoma cells.
According to a study from Spain, "Clonal idiotypic immunoglobulins of follicular lymphomas can be isolated by somatic fusion procedures. Idiotypic IgMs (Id-IgM) were isolated from two patients and used to immunize a strain of mice, deficient in mouse antibody production and engineered with yeast artificial chromosomes (YAC) containing fragments of the human immunoglobulin (Ig) mu/delta heavy chain and kappa/lambda light chain loci. Sequence analysis showed that hybridomas prepared from spleen cells of immunized mice expressed exclusively one of the six VH genes (VH1-2) present in the YAC transgene with different D/J rearrangements, and secrete fully human monoclonal antibodies (mAb) that recognized the tumor-specific IgM proteins."
"Further studies of the reactivity of the monoclonal anti-human Id-IgM antibodies revealed that they are specific for the individual protein of each patient and probably react with idiotypic determinants," said Eduardo Suarez and colleagues at the Hospital Clinica Puerta de Hierro. "In one case studied, the antibody recognized specifically the ...
- Reportlinker Adds Therapeutic Monoclonal Antibodies Markets.
- Press release article from: Business Wire June 3, 2009 700+ words
...Reportlinker Adds Therapeutic Monoclonal Antibodies Markets http://www.reportlinker...Reportlinker-Adds-Therapeutic-Monoclonal-Antibodies-Markets.html Antibodies are...leaving healthy cells unaffected, monoclonal antibodies can serve to diagnose and treat...
- Research and Markets: The Global Monoclonal Antibodies Market Was Valued At...
- Press release article from: Business Wire December 2, 2009 700+ words
...addition of the "The Future of Monoclonal Antibodies - Market Forecasts to 2015, Competitive...their offering. "The Future of Monoclonal Antibodies - Market Forecasts to 2015, Competitive...essentially provides insights on the monoclonal antibodies market potential, actual sales...
- Findings in monoclonal antibodies reported from Hebrew University, Department...
- Newspaper article from: Vaccine Weekly July 1, 2009 700+ words
Fresh data on monoclonal antibodies are presented in the report 'Three decades of human monoclonal antibodies: past, present and future developments...reproducible method for producing rodent monoclonal antibodies but poor results were obtained...
- Visiongain is proud to announce the release of the brand new reprot...
- Press release article from: M2 Presswire March 30, 2009 700+ words
...brand new reprot "Therapeutic Monoclonal Antibodies Report 2008-2023"(C)1994...the global market for therapeutic monoclonal antibodies. While the pharmaceutical industry...generics industry, the segment of monoclonal antibodies therapeutics is thriving and growing...
- New Product Launches Set to Unleash Multiple Growth Avenues in U.S. Monoclonal...
- Press release article from: Business Wire June 9, 2008 700+ words
...Calif. -- The U.S. therapeutic monoclonal antibodies market is poised for a quantum...S. Biotechnology - Therapeutic Monoclonal Antibodies Market, finds the market earned...with an overview of the U.S. Monoclonal Antibodies Market, send an e-mail to Johanna...
- Trends developed in Therapeutic Monoclonal Antibodies Market.
- Press release article from: M2 Presswire June 16, 2009 700+ words
...developed in Therapeutic Monoclonal Antibodies Market(C)1994-2009...com included Therapeutic Monoclonal Antibodies Markets report that discusses the application of monoclonal antibodies in therapeutic areas. Therapeutic...
- Therapeutic Monoclonal Antibodies Markets Report Reviews the Market for Medical...
- Newspaper article from: Cancer Weekly June 23, 2009 700+ words
...the addition of the "Therapeutic Monoclonal Antibodies Markets" report to their offering...leaving healthy cells unaffected, monoclonal antibodies can serve to diagnose and treat...Indeed, the field of therapeutic monoclonal antibodies potentially has far-reaching...
- Reportlinker Adds Monoclonal Antibodies: Pipeline Analysis and Competitive...
- Newspaper article from: U.S. Newswire October 26, 2009 700+ words
...its catalogue. Reportlinker Adds Monoclonal Antibodies: Pipeline Analysis and Competitive...p0156557/Reportlinker-Adds- Monoclonal-Antibodies-Pipeline-Analysis-and-Competitive...focus on "engineered" antibodies Monoclonal Antibodies: Pipeline Analysis and Competitive...
Source: HighBeam Research, Monoclonal antibodies recognize idiotypic immunoglobulins of lymphoma...