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Streptococcus pneumoniae neuraminidase protects against otitis media.
2004 SEP 1 - (NewsRx.com & NewsRx.net) -- Immunization with native or recombinant Streptococcus pneumoniae neuraminidase affords protection in the chinchilla otitis media model.
According to recent research from the United States, "Streptococcus pneumoniae neuraminidase has been implicated as a virulence factor in the pathogenesis of pneumococcal otitis media. In this study, native neuraminidase was partially purified from cultures of S. pneumoniae by serial chromatography with DEAE-Sepharose and Sephacryl S-200. Recombinant neuraminidase, a 3,038-bp fragment of the neuraminidase A (nanA) gene, was cloned into the pET-28b vector and then expressed at high levels in Escherichia coli."
"Chinchillas were immunized subcutaneously with either the gel-purified native or recombinant neuraminidase, and all responded with elevated titers of antineuraminidase antibody in serum," stated James P. Long and colleagues at Ohio State University. "Immunization with neuraminidase resulted in a significant reduction in nasopharyngeal colonization as well as in the incidence of otitis media with effusion. These data demonstrate for the first time that neuraminidase ...
- Streptococcus pneumoniae neuraminidase protects against otitis media.
- Newspaper article from: Proteomics Weekly August 30, 2004 700+ words
...Streptococcus pneumoniae neuraminidase affords protection...chinchilla otitis media model. According...Streptococcus pneumoniae neuraminidase has been...Streptococcus pneumoniae neuraminidase affords protection...chinchilla otitis media model. Infec...
- Otitis media (ear infection): updated October 2000.(Pamphlet)
- Newspaper article from: Pamphlet by: National Institute on Deafness and Other Communication Disorders October 8, 2000 700+ words
* What is otitis media? * How do we hear? * Why are more children affected by otitis media than adults? * What are the effects of otitis media? * How can someone tell if a child has otitis media? * Can anything be done to prevent otitis media...
- Otitis Media
- Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Carson-DeWitt, Rosalyn; Frey, Rebecca January 1, 2006 700+ words
Otitis Media Definition Otitis media is an infection of the middle ear space, behind the eardrum...middle ear will be helpful for understanding the development of otitis media. The external ear canal is that tube which leads from the outside...
- Correlation between otitis media and craniofacial morphology in adults.
- Magazine article from: Ear, Nose and Throat Journal Di Francesco, Renata C. Sampaio, Perboyre Lacerda Bento, Ricardo Ferreira December 1, 2007 700+ words
...study to determine if the development of otitis media in adults is correlated with craniofacial...40 years; 32 of these patients had otitis media and 34 did not. All subjects underwent...the cephalometric measurements in the otitis media group and the control group revealed...
- Middle ear infections in children: brouhaha over treatment leads to consensus -...
- Magazine article from: Science News Brooks, Adrienne C. November 19, 1994 700+ words
...painful infection of the middle ear, or otitis media, have become more sophisticated than...generated high-decibel controversy. Otitis media ranks second only to the common cold...born in the United States will develop otitis media by age 2. Most of them will outgrow...
- Adenotonsillectomy is Ineffective in Preventing Recurrent Acute Otitis...
- Newspaper article from: Pediatric & Adolescent Medicine Reports January 1, 2000 700+ words
...Ineffective in Preventing Recurrent Acute Otitis Media Source: Paradise JL, et al. Adenoidectomy...adenotonsillectomy for recurrent acute otitis media: Parallel randomized clinical trials...occurrence of persistent or recurrent otitis media. Paradise and associates at the Childrens...
- Rethinking Automatic Treatment of Otitis Media with Antibiotics.(Clinical...
- Newspaper article from: Pediatric & Adolescent Medicine Reports September 1, 1997 700+ words
Rethinking Automatic Treatment of Otitis Media with Antibiotics ABSTRACT & COMMENTARY...clinical course of children with acute otitis media indicate that there is only a small...initial treatment for children with acute otitis media? A meta-analysis. BMJ 1997;314...
- New Vaccine Could Reduce Acute Otitis Media Episodes in Children by 6-8%,...
- Press release article from: PR Newswire September 6, 2000 700+ words
...announces the publication of a new study titled Otitis Media. Otitis media, defined as inflammation or infection of the...has contributed to an increased prevalence of otitis media within the pediatric population. Approximately...
