Perinatal HIV-1 infection despite maternal anti-HIV-1 neutralizing antibody. (Research Report)

AUTHORS: K. Krasinski, Y. Cao, A. Fidelia, D. Bebenroth, A. Friedman and W. Borkowsky. New York University Medical Center, Bellevue Hospital.

According to an abstract submitted by the authors to a joint meeting of the Association for American Physicians, American Society for Clinical Investigation and American Federation for Clinical Research, held May 1-4, 1992, in Baltimore, Maryland, "Anti-HIV-1 total and neutralizing (NEUT) antibody in the serum of 28 HIV-1 infected mothers at delivery, was correlated with infant HIV-1 infection. Total anti-HIV-1 antibody was tested using standard EIA. NEUT activity against HTLV-III-RF and HIV-1-JR-FL was determined using a …