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Combination gene therapy staunches melanoma growth and metastasis.

Health & Medicine Week

| August 23, 2004 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 AUG 23 - (NewsRx.com & NewsRx.net) -- Combination gene therapy staunches melanoma growth and metastasis.

According to a study from South Korea, "transfection of the antiangiogenic angiostatin and endostatin genes was shown to be an alternative to high-dose administration of angiostatin or endostatin proteins for cancer therapy. We have systematically investigated whether coadministration of the mouse angiostatin kringle 1-3 gene (pFLAG-AngioK1/3) and the endostatin gene (pFLAG-Endo) complexed with cationic liposomes exhibits enhanced therapeutic efficacy."

"In vitro, the coexpressed mixture of angiostatin K1-3 and endostatin more effectively reduced…

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Source: HighBeam Research, Combination gene therapy staunches melanoma growth and metastasis.

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