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Heart Failure Drug Offers Little Benefit In Mixed-Race Group; But A New Study Opens Doors; The latest data show BiDil, which contains nitric oxide, helps African Americans.(HEALTH & MEDICINE)
Byline: AMY REEVES
When NitroMed recently announced that its heart-failure drug BiDil showed strong trial results, Wall Street smelled money. The stock price tripled the next week.
That wasn't the only reason BiDil made news. It also was the first heart drug tested entirely on African-Americans.
Black Americans suffer a higher rate of heart disease than any other ethnic group. Though they make up only 11% of the population, they bear 18% of the heart-disease burden. Yet heart medicines have not served them as well.
By and large, blacks seem to have the disease for different reasons than other ethnic groups. It's more likely related to hypertension than it is to coronary blockage.
Blacks take standard drugs such as Ace inhibitors, yet studies show those drugs don't work as well on them as on others.
The first developers of BiDil weren't even looking to make a drug for blacks.
- NitroMed Announces Launch of BiDil(R) for the Treatment of Heart Failure in...
- Press release article from: Business Wire July 1, 2005 700+ words
...LEXINGTON, Mass. -- NitroMed, Inc. (NASDAQ...for the treatment of heart failure in black patients as...insurance status. "NitroMed is pleased to be able...the African American Heart Failure Trial (A-HeFT...approval. This speaks to NitroMed's sense of urgency...
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- Press release article from: Business Wire December 23, 2004 700+ words
...Medical Officer for NitroMed. "We look forward...disproportionately burdened by heart failure and historically...Americans living with heart failure." About BiDil...development for NitroMed, BiDil is an orally...the treatment of heart failure in African ...
- NitroMed's BiDil Approved For Heart Failure In Black Patients.
- Magazine article from: BIOWORLD Today November 3, 2009 700+ words
...approved BiDil, NitroMed Inc.'s heart failure treatment for black...percent surge in NitroMed's stock, and those...Co-sponsored by NitroMed and the Association...first conducted in a heart failure population in which...
- NITROMED ROUND NETS $31M TO FUND HEART FAILURE DRUG.(Brief Article)
- Magazine article from: BIOWORLD Today Coghill, Kim June 15, 2001 700+ words
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- Press release article from: Business Wire September 21, 2005 700+ words
...RATON, Fla. -- NitroMed, Inc. (NASDAQ...meeting of the Heart Failure Society of America...African American Heart Failure Trial (A-HeFT...sponsored by NitroMed and the Association...and launched by NitroMed, Inc. in July...hospitalization for heart failure and ...
- NitroMed receives FDA approval for BiDil heart failure drug to treat...
- Newspaper article from: Transplant News July 15, 2005 700+ words
NitroMed, Inc., Lexington...treatment of heart failure in self-identified...hospitalization for heart failure compared to...market BiDil, NitroMed was strongly...80 a day. NitroMed responded by...000 black heart failure patients with...
- NitroMed BiDil for heart failure.(Noted)
- Magazine article from: Pharmaceutical Processing May 1, 2005 700+ words
NitroMed BiDil for heart failure: FDA's Cardiovascular & Renal...Committee will meet June 16 to evaluate NitroMed's BiDil for treatment of heart failure in African-Americans. NitroMed resubmitted the BiDil NDA with new data...
- NitroMed Stops Heart Failure Study -A-HeFT- in African Americans Due to...
- Press release article from: Business Wire July 19, 2004 700+ words
...Discuss A-HeFT NitroMed, Inc. (NASDAQ...Americans with heart failure. The trial was...Manuel Worcel, NitroMed's Chief Medical...African American heart failure patients is consistent...Black Cardiologist Heart Failure Steering Committee...and C.E.O., NitroMed ...