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2004 AUG 5 - (NewsRx.com & NewsRx.net) -- Continued injection drug use is not associated with a progression to AIDS in infected women.
"Data from a prospective, multicentered study of HIV infection in women (HIV Epidemiology Research Study [HERS]) was analyzed to investigate the effect of continued injection drug use behaviors on progression to AIDS.
"All women enrolled in the HERS had at enrollment and at 6-month intervals, a face-to-face interview that included specific injection drug use, a physical exam and specimen collection that included T-cell subset analysis and HIV plasma RNA detection," scientists writing in the International Journal of STD & AIDS report.
"Six hundred and thirty-nine HIV-infected women contributed 3021 person years of observation during 7.25 years of follow-up, and 299 of these women progressed to AIDS (46.8%).
"In multivariable analysis," A.M. Rompalo and coworkers wrote, "there was no significantly increased risk of progression to AIDS for women reporting prebaseline injection drug use [hazard ratio (HR)=1.07 (0.78, 1.47)] or reported injection drug use during follow-up [HR=0.89 (0.66, 1.21)] compared with never injecting."
Rompalo continued, "In a separate multivariable-model, comparing women who reported no injection in past 6 months to active injection drug users, the frequency of injection during the previous 6 ...
Source: HighBeam Research, Continued injection drug use not associated with progression to AIDS...