AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.

NMR and GGE not necessarily interchangeable in women and diabetic patients.

Women's Health Weekly

| August 05, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 AUG 5 - (NewsRx.com & NewsRx.net) -- A study comparing agreement between nuclear magnetic resonance (NMR) and gradient gel electrophoresis (GGE) for measuring low-density lipoprotein (LDL) particle size found the two techniques are not necessarily interchangeable in women and patients with diabetes.

D.R. Witte and colleagues at the Royal Free & University College of London "measured LDL size by NMR and GGE in 324 individuals (152 with type 1 diabetes and 172 controls)."

They reported, "The Spearman correlation between both methods was 0.39 [95% confidence interval (CI)=0.29, 0.48]. The average difference was 5.38 nm (NMR being smaller), but it increased with increasing LDL size. Less than 50% of people classified as pattern B on GGE were classified as pattern B on NMR (K=0.31; 95% CI=0.17, 0.45)."

Their analysis revealed lower agreement "for diabetic subjects compared with controls, for women compared with men and for subjects with triglycerides <1.30 mmol/L compared with subjects with triglycerides>1.30 mmol/L."

"External validation showed that cholesteryl ester transfer rate was related to LDL size on GGE in all subgroups and to LDL size on NMR only in men and nondiabetic subjects," the researchers said.

They noted, therefore, that ...

Related articles from newspapers, magazines, journals, and more
Genetic loci linked to LDL size and TG levels in FHTG identified.
Newspaper article from: Heart Disease Weekly January 18, 2004 700+ words
...NewsRx.net) -- Genetic loci linked to LDL size and TG levels in FHTG patients have been...a whole-genome scan for linkage to LDL size and triglyceride (TG) levels in 26 kindreds...familial hypertriglyceridemia (FHTG)." "LDL size was estimated using gradient gel electrophoresis...
Soy protein favorably affects LDL size independently of isoflavones in...
Magazine article from: Alternative Medicine Review June 1, 2004 700+ words
Desroches S, Mauger JF, Ausman LM, et al. J Nutr 2004;134:574-579. We assessed the independent effect of soy protein relative to animal protein and of isoflavones on various electrophoretic characteristics of LDL particles. LDL particles were characterized by polyacrylamide gradient gel
Beta[subscript]3-adrenergic receptor gene polymorphism associated with reduced...
Newspaper article from: Heart Disease Weekly May 18, 2003 700+ words
2003 MAY 18 - (NewsRx.com & NewsRx.net) -- The polymorphism of the beta[subscript]3-adrenergic receptor gene is associated with a reduced low-density lipoprotein particle size. According to published research from Japan, "People with a predominance of small, dense low-density lipoprotein (LDL)
NMR: an MVP in spectroscopy: nuclear magnetic resonance (NMR) spectroscopy is...
Magazine article from: R & D Walz, Martha August 1, 2007 700+ words
Nuclear magnetic resonance (NMR) spectroscopy allows scientists to see...ultra-high magnetic field created by the NMR magnet. Once in the magnetic field, atoms...bow it interacts with other molecules. NMR spectroscopy is reliable, predictable...
NMR Spectroscopy Report Introduces Students To Modern NMR As Applied To...
Press release article from: M2 Presswire November 15, 2007 700+ words
...15 November 2007-Research and Markets: NMR Spectroscopy Report Introduces Students To Modern NMR As Applied To Analysis Of Organic Compounds...reports/c74453) has announced the addition of "NMR Spectroscopy Explained : Simplified Theory...
NMR Spectroscopy 101.(Brief Article)
Magazine article from: R & D Maas, Werner November 1, 2000 700+ words
Nuclear magnetic resonance (NMR) spectroscopy has experienced a tremendous...at Harvard Univ., also in Cambridge, NMR spectroscopy has developed into one of today...introduction of pulsed Fourier transform NMR spectroscopy (as opposed to continuous...
NMR: the competitive challenges increase.(Statistical Data Included)
Newspaper article from: Instrument Business Outlook June 30, 2002 700+ words
NMR (nuclear magnetic resonance) has the distinction...costing as much as $5 million. Designing an NMR spectrometer, which involves working with...has accelerated the development of high-end NMR more in recent years than drug discovery and...
NMR of America reports results of operations for second fiscal quarter and six...
Press release article from: Business Wire November 13, 1995 700+ words
...BUSINESS WIRE)--Nov. 13, 1995--NMR of America Inc. (Nasdaq/NMS:NMRR...Commenting on the results, Joseph Guy Dasti, NMR's president and chief executive officer...represents the sixth consecutive quarter in which NMR's net revenues have shown significant...
For more facts and information, see all results
©2009 Gale, a part of Cengage Learning. All rights reserved.
About us | FAQs | Contact us | Privacy policy | Terms and conditions
Other Gale sites: Encyclopedia.com | HighBeam Research | Acquire Content | Books & Authors | Goliath | MovieRetriever | Smart QandA