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Glycol chitosan improves efficacy of bovine herpesvirus vaccine.
2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Glycol chitosan improves the efficacy of intranasally administrated replication defective human adenovirus type 5 expressing glycoprotein D of bovine herpesvirus 1.
According to published research from Belgium, "The ability of two soluble formulations, namely chitosan and glycol chitosan, when used as an intranasal adjuvant, to improve the immunogenicity of an intranasal human adenovirus type 5 replication defective expressing bovine herpesvirus 1 (BoHV-1) glycoprotein D based vaccine, was investigated in cattle. Their adjuvant effects on immune response by increasing clinical and especially virological protection against an intranasal BoHV-1 challenge were then evaluated."
"The best virological protection was obtained in calves immunized with the vaccine vector adjuvanted with glycol chitosan which decreased the challenge BoHV-1 virus excretion titers by 0.5-1.5 log when compared to those obtained in calves immunized with the vaccine vector alone or adjuvanted with chitosan," said Sacha Gogev and colleagues at the University of Liege and KitoZyme S.A. "A slight difference in clinical scores was observed in calves immunized with the adjuvanted vaccine vector compared to calves immunized with the ...
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- Newspaper article from: Hematology Week May 3, 2004 700+ words
...com & NewsRx.net) -- Bovine herpesvirus 4 persistently infects neuronal cells in vitro. "Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus...in Journal of Neurovirology (Bovine herpesvirus 4 infects differentiated neuronal...
- Bovine herpesvirus VP22 enhances neuroblastoma self-destruction.
- Newspaper article from: Biotech Week June 9, 2004 700+ words
...com & NewsRx.net) -- Bovine herpesvirus VP22 enhances neuroblastoma self...mammalian expression vectors carrying bovine herpesvirus 1 (BHV-1) VP22 (BVT22) or herpes...their study in Journal of Virology (Bovine herpesvirus tegument protein VP22 enhances thymidine...
- Tests for antibodies against bovine herpesvirus 1 evaluated.
- Newspaper article from: Science Letter November 30, 2004 700+ words
...evaluated tests for antibodies against bovine herpesvirus 1 performed in national reference...sets contained the three European bovine herpesvirus 1 (BHV1) reference serum samples...Evaluation of tests for antibodies against bovine herpesvirus 1 performed in national reference...
- Latency-related gene of bovine herpesvirus-1 disables productive...
- Newspaper article from: Virus Weekly February 18, 2003 700+ words
...the United States, "transfection of bovine cells with bovine herpesvirus-1 genomic DNA yields low levels of infectious virus...Journal of General Virology (The latency-related gene of bovine herpesvirus-1 can inhibit the ability of blCPO to activate productive...
- Latency-related gene of bovine herpesvirus-1 disables productive infection.
- Newspaper article from: Gene Therapy Weekly February 20, 2003 700+ words
...the United States, "transfection of bovine cells with bovine herpesvirus-1 genomic DNA yields low levels of infectious virus...Journal of General Virology (The latency-related gene of bovine herpesvirus-1 can inhibit the ability of blCPO to activate productive...
- Self-assembled nanoparticles shepherd RGD peptide to tumor vessels.
- Newspaper article from: Obesity, Fitness & Wellness Week May 29, 2004 700+ words
...peptide, hydrophobically modified glycol chitosan (HGC) capable of forming nano...cholanic acid to the main backbone of glycol chitosan. The RGD peptide labeled with fluorescein...amino groups in the main backbone of glycol chitosan," explained J.H. Park and colleagues...
