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Immunomodulatory action of mycobacterial secretory proteins reviewed.
2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists review the immunomodulatory action of mycobacterial secretory proteins in a recent issue of the journal Microbes and Infection.
According to a study from India, "The recently discovered RD1 locus encodes proteins that are actively secreted by pathogenic mycobacteria, including Mycobacterium tuberculosis. Since they are missing in non-tuberculous mycobacteria, these proteins are promising not only as candidates for vaccination and diagnostic tests, but also in understanding mycobacterial evasion of protective immunity in susceptible individuals."
"Here we analyze the possible role of M. tuberculosis secretory proteins in immunity against tuberculosis, with emphasis on their immunomodulatory action and the potential involvement in mycobacterial subversion of the host immune defense," wrote Vladimir Trajkovic and colleagues at the International Center for Genetic ...
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Source: HighBeam Research, Immunomodulatory action of mycobacterial secretory proteins reviewed.