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Antibody isotype patterns to Schistosoma antigens identified.
2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Scientists have identified antigen-specific antibody isotype patterns to Schistosoma japonicum recombinant and native antigens in a defined population in Leyte, the Philippines.
According to recent research from the Philippines and Australia, "We describe antibody isotype patterns resulting from Schistosoma japonicum infection among 155 individuals 5-76 years old from a community in Leyte, The Philippines. Their exposure, infection, and re-infection status had been observed in a previously described water contact study used to categorically classify them as putative resistant or susceptible individuals. Antigens tested for specific antibody isotype responses were soluble worm antigen preparation (SWAP) and soluble egg antigen (SEA) and a panel of recombinant molecules."
"The study was aimed primarily at evaluating antigen-specific antibody responses and their potential in inducing protection among putative resistant individuals," said Luz P. Acosta at the Research Institute for Tropical Medicine in the Philippines and collaborators in the Philippines and Australia. "Specific antibody responses suggestive of an involvement in protection were an IgE response to SWAP among females less than 20 years of age (5-19) and IgA ...
- Antibody isotype patterns to Schistosoma antigens identified.
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