AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Reduced L-selectin expression identifies tumor-specific type 1 T cells.
2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Reduced L-selectin (CD62L[superscript]Low) expression identifies tumor-specific type 1 T cells from lymph nodes draining an autologous tumor cell vaccine.
"Reduced expression of CD62L can identify tumor-specific T cells in lymph nodes draining murine tumors. Here, we examined whether this strategy could isolate tumor-specific T cells from vaccinated patients. Tumor vaccine-draining lymph node (TVDLN) T cells of seven patients were separated into populations with reduced (CD62L[superscript]Low) or high levels of CD62L (CD62L[superscript]High)," scientists writing in the journal Cellular Immunology report.
"Effector T cells generated from CD62L[superscript]Low cells maintained or enriched the autologous tumor-specific type 1 cytokine response compared to unseparated TVDLN T cells in four of four patients showing tumor-specific cytokine secretion," stated Sybren L. Meijer and collaborators at the Providence Portland Medical Center. "Interestingly, effector T cells generated froth CD62L[superscript]Low or CD62L[superscript]High TVDLN were polarized towards a dominant type 1 or type 2 cytokine profile, respectively. For CD62L[superscript]Low T cells the type 1 cytokine profile appeared determined prior to ...
- Study data from S. Lauer and colleagues update understanding of cellular...
- Newspaper article from: Cardiovascular Week April 27, 2009 700+ words
...results of their research in Cellular Immunology (Soluble MD2 increases...epithelial cell surface. Cellular Immunology, 2009;255(1-2...publisher of the journal Cellular Immunology can be contacted at...
- Hollis-Eden Pharmaceuticals Appoints Cellular Immunology Scientific...
- Press release article from: PR Newswire December 16, 1999 700+ words
...appointment of Charles Dowding, PhD, to the position of Cellular Immunology Scientific Investigator. Dr. Dowding comes to the Company...planning and implementation of research strategies in cellular immunology and pre-clinical research. As a member of the company...
- Data on gene therapy discussed by investigators at German Cancer Research...
- Newspaper article from: Cancer Vaccine Week October 27, 2008 700+ words
...colleagues, German Cancer Research Center, Division of Cellular Immunology (see also Gene Therapy). The researchers concluded...Janke, German Cancer Research Center, Division of Cellular Immunology, D-69120 Heidelberg, Germany. The publisher of the...
- Interleukin-12 (IL-12) augments cytolytic activity of natural killer cells...
- Newspaper article from: AIDS Weekly Denis, M. September 12, 1994 700+ words
SOURCE: Cellular Immunology, July 1994;156(2):529-536. According to the author's abstract of an article published in Cellular Immunology, "We tested the impact of interleukin-12 (IL-12) and of cytotoxic leukocytes (particularly...
- Cylex Incorporated Closes $6.4 Million in Second Round of Private Financing;...
- Press release article from: PR Newswire September 7, 2004 700+ words
...model and the importance of being first to market with a cellular immunology assay," said Judith A. Britz, Ph.D., chairman...to the production of ImmuKnow(TM), the company's cellular immunology assay, in June. About Cylex Cylex is a life science...
- Multiple CTL specificities against autologous HIV-1-infected BLCLs....
- Newspaper article from: AIDS Weekly Aheame, P.M. Morgan, R.A. Sebastian, M.W. Bolognesi, D.P. Weinhold, K.J. April 17, 1995 700+ words
According to the authors' abstract of an article published in Cellular Immunology, "The cellular immune response to HIV-1 has been well studied but, in many respects, remains incompletely defined. Although...
- Institute Jean Godinot and Guava Technologies Demonstrate Superiority of...
- Press release article from: Business Wire June 16, 2003 700+ words
...time-consuming and tedious manual microscopy methods, which currently represent a "gold standard" method for cellular immunology research. Jacky Bernard, Ph.D. and Anne-Laure Millard, Ph.D. of the Institut Jean Godinot recently...
- Bosnian arrested by Sfor for possessing "a specific type of weapon".
- News wire article from: Asia Africa Intelligence Wire May 30, 2004 700+ words
...municipality of Modrica, at 0900 [0700 gmt] after allegedly finding "a specific type of weapon" in his house. "According to his family members, Sfor found `a specific type of weapon' in his house while conducting Operation Harvest, aimed...
- High-sodium diets may contribute to a specific type of cataract.
- Magazine article from: Environmental Nutrition June 1, 2000 700+ words
High-sodium diets may contribute to a specific type of cataract, according to a study of over 2,800 middle-age and older Australians. Those with the highest sodium intake had...
- Incidence of Specific Type of Breast Cancer Rising Dramatically; Treatment...
- Press release article from: Business Wire March 26, 1996 700+ words
SAN FRANCISCOBUSINESS WIREMarch 26, 1996--Since the early 1980s, reported cases of "ductal carcinoma in situ" (DCISmalignant cells confined to the breast's milk ducts--have increased dramatically, according to a report from UC San Francisco and the affiliated San Francisco VA Medical Center.
Source: HighBeam Research, Reduced L-selectin expression identifies tumor-specific type 1 T...