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Buruli ulcer disease in Cameroon rediscovered.

Vaccine Weekly

| August 04, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 AUG 4 - (NewsRx.com & NewsRx.net) -- Researchers have rediscovered Buruli ulcer disease in Cameroon.

According to published research from Cameroon and Belgium, "To assess the magnitude of the Buruli ulcer (BU) problem in Cameroon, we conducted a cross-sectional survey in the Nyong River basin and identified on clinical grounds a total of 436 cases of active or inactive BU (202 and 234, respectively). Swab specimens were taken from 162 active cases with ulcerative lesions and in 135 of these (83.3%) the clinical diagnosis was confirmed by the IS2404 polymerase chain reaction."

"Most lesions (93%) were located on the extremities, with lower limbs being twice as commonly involved as upper limbs," reported Jurgen Noeske at the Centre Pasteur du Cameroun in Cameroon and collaborators in Cameroon, Switzerland, and Belgium. "The age of patients with active BU ranged from 2 to 90 years with a median age of 14.5 years. Vaccination with bacilli Calmette-Guerin appeared to protect children against more severe forms of BU with multiple lesions. We ...

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