Oral lesions in HIV-infected children signal need for more aggressive treatment. (University of California, San Francisco)

University of California, San Francisco

The presence of oral lesions in HIV-infected children may offer important clues about survival and signals the need for more aggressive treatment of the HIV infection, say clinicians who studied a group of infected children.

The investigation, which took place at the University of Miami and the Oral AIDS Center at the University of California at San Francisco (UCSF), involved 99 children with perinatally acquired HIV infection. While oral lesions are a common clinical sign of HIV infection in children, little is known about their prognostic significance. Researchers do know that among HIV-infected adults, two types …