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Hormone therapy raises risk of mental decline for some women.

The Philadelphia Inquirer (Philadelphia, PA)

| May 27, 2003 | COPYRIGHT 2007 The Philadelphia Inquirer. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Byline: Marie McCullough

PHILADELPHIA _ In the latest blow to hormone therapy, a large federal study has found that long-term use doubles the risk of dementia in postmenopausal women, dimming hopes that hormones might ward off Alzheimer's disease.

A companion analysis found that taking the sex hormones estrogen and progestin for five years does not enhance mental functioning, and may even result in mental decline for some postmenopausal women.

"This study just looked at women aged 65 to 79, so it doesn't say that if you're a 50-year-old woman taking hormones for menopausal symptoms, you're putting yourself at risk of dementia," said co-author Jennifer Hays, a developmental psychologist at Baylor College of Medicine. "It does say, certainly, this is…

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