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Lipitor reduces heart attacks and strokes in study patients with diabetes.

Biotech Business Week

| July 05, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JUL 5 - (NewsRx.com & NewsRx.net) -- Pfizer Inc's cholesterol-lowering medicine, Lipitor, significantly reduced heart attacks and strokes in patients with diabetes, according to data presented from the largest study specifically designed to study a statin in this patient population.

Results were presented at the annual meeting of the American Diabetes Association.

In the Collaborative Atorvastatin Diabetes Study (CARDS), which involved more than 2,800 patients with type-2 diabetes, no history of heart disease, and relatively-low levels of cholesterol, patients who took Lipitor had a 37% reduction in major cardiovascular events, which included heart attacks, stroke, chest pain that required hospitalization, cardiac resuscitation, and coronary revascularization procedures.

In addition, 48% fewer Lipitor-treated patients experienced strokes compared to those who received placebo, and the overall mortality rate for Lipitor patients was 27% lower than for those on placebo.

The CARDS study was stopped nearly 2 years earlier than planned because of the significant benefits among patients who took Lipitor compared with those who received placebo.

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