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pH-sensitive toxins find application in vaccines and drug delivery.
2004 JUL 7 - (NewsRx.com & NewsRx.net) -- pH-sensitive toxins are finding application in vaccines and drug delivery.
"pH-sensitive toxins are secreted by bacteria and reach the cytosol of eukaryotic target cells by complex mechanisms involving receptor binding, membrane interaction, and translocation across a cell lipid membrane. Membrane interaction and ability to reach the cytoplasm have been used respectively to present proteins at the cell surface and to transport foreign peptides or DNA into the cytoplasm. The first approach is used in anticancer vaccination and the second in inducing a major histocompatibility (MHC) class I presentation of exogenous peptides or proteins," scientists in Belgium report.
"A brief overview of the use of toxins themselves for targeting cancer cells is also presented," said Veronique Cabiaux at the Free University of Brussels. "Altogether, the data suggest that pH sensitive toxins have a huge potential for surface presentation or cytosol transport of biomacromolecules and that ...
- pH-sensitive toxins find application in vaccines and drug delivery.
- Newspaper article from: Drug Week July 9, 2004 700+ words
...NewsRx.net) -- pH-sensitive toxins are finding application in vaccines and drug delivery. "pH-sensitive toxins are secreted by bacteria...review in Advanced Drug Delivery Reviews (PH-sensitive toxins: interactions with...
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...2008-Research and Markets: Leading Drug Delivery Companies and Technologies: Competitive...announced the addition of the "Leading Drug Delivery Companies and Technologies: Competitive...delivery system continues to dominate the drug delivery market due to convenient usage, cost...
- Drug Delivery Technologies 2004 Conference Technical Agenda Unveiled Featuring...
- Press release article from: PR Newswire June 16, 2004 700+ words
...organizers of the "9th International Drug delivery Technologies & Deal-Making...agenda that features a record number of drug delivery company presentations organized around...following panel topics populated by drug delivery, biotech, and specialty pharma companies...
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- Newspaper article from: Diabetes Week August 18, 2008 700+ words
...announced the addition of the "Leading Drug Delivery Companies and Technologies: Competitive...delivery system continues to dominate the drug delivery market due to convenient usage, cost...safe propellant delivery. Leading Drug Delivery Companies and Technologies Over the...
- Reportlinker Adds Drug Delivery Markets: Implantable / Injectable and...
- Press release article from: PR Newswire September 24, 2009 700+ words
...report is available in its catalogue. Drug Delivery Markets: Implantable / Injectable...www.reportlinker.com/p0148033/Drug-Delivery-Markets-Implantable-/-I njectable...lifetime of their biggest products, drug delivery has become an important focus of the...