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Tuberculin-boosted antibodies correlate with immunity in cattle.
2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Tuberculin-boosted antibody responses correlate with pathology and cell-mediated immunity in cattle vaccinated with Mycobacterium bovis BCG and infected with M. bovis.
According to published research from the United States, U.K., and Denmark, "Vaccine development and our understanding of the pathology of bovine tuberculosis in cattle would be greatly facilitated by definition of the immunological correlates of protection and/or pathology. In this study we analyzed humoral immune responses in Mycobacterium bovis BCG-vaccinated and control cattle (in particular, the relationship between the intradermal comparative tuberculin skin test and serum immunoglobulin G [IgG] responses) against a range of mycobacterial antigens (MPB59, MPB64, MPB70, MPB83, ESAT-6, CFP-10, Acr1, and PstS-1) by multiantigen print immunoassay and conventional enzyme-linked immunosorbent assay."
"Following M. bovis infection, the comparative tuberculin skin test strongly boosted IgG, IgG1, and IgG2 antibody responses, particularly against MPB83 and MPB70, in unvaccinated cattle but failed to boost these responses, or did so only weakly, in BCG-vaccinated calves," reported Konstantin Lyashchenko at Chembio Diagnostic Systems, Inc. in the U.S. and collaborators in the U.S., U.K., and Denmark. "In addition, the skin test-induced increases in MPB83-specific IgG responses correlated ...
- DNA Vaccine Produces Antibody Responses to Brugia malayi Antigens.(Brief...
- Newspaper article from: Vaccine Weekly February 16, 2000 700+ words
...com) -- DNA vaccination produces antibody responses to single and multiple Brugia malayi...In the present study, murine antibody responses were studied after monovalent or...title of their presentation was "Antibody Responses to Single and Multiple Brugia malayi...
- "Antibody Responses to Single and Multiple Brugia malayi Antigens After DNA...
- Newspaper article from: Vaccine Weekly February 15, 1999 700+ words
...antigens. In the present study, murine antibody responses were studied after DNA vaccination...but not to the other antigens. Antibody responses were more consistent after HGG than...vaccination. HGG produced stronger antibody responses than IM for some but not all antigens...
- B7 costimulatory molecules play role in antibody responses to Salmonella.
- Newspaper article from: Life Science Weekly December 7, 2004 700+ words
...in mediating systemic and mucosal antibody responses to attenuated Salmonella enterica...mucosal and systemic anti-Salmonella antibody responses after a single immunization, while...exhibited suppressed anti-Salmonella antibody responses following the second immunization...
- Antibody Responses Absent in HIV Exposed Uninfected Sex Workers.
- Newspaper article from: Vaccine Weekly August 16, 2000 700+ words
...NewsRx.com) -- Specific mucosal antibody responses were not found in sex workers from...individuals, HIV specific mucosal antibody responses may exist and play a role in resistance...HIV-1 envelope specific mucosal antibody responses in HIV resistant sex workers in west...
- Antibody responses to Wolbachia surface protein characterized.
- Newspaper article from: Drug Week October 31, 2003 700+ words
...com & NewsRx.net) -- The antibody responses to Wolbachia surface protein have...chronic filarial disease in humans, antibody responses to Wolbachia surface protein (WSP...report. "As opposed to antifilarial antibody responses, which were largely influenced by...
- ProQuad-R-, Merck's Investigational Combination Vaccine, Resulted in Antibody...
- Press release article from: Business Wire May 13, 2004 700+ words
...varicella (chickenpox) resulted in antibody responses similar (non inferior) to those...Vaccine Live (Oka/Merck)). Antibody responses and tolerability data from this study...could help children achieve similar antibody responses to these viruses compared to the...
- Vaccine Induces Specific Mucosal Antibody Responses in Humans.(Brief Article)
- Newspaper article from: Vaccine Weekly March 29, 2000 700+ words
...systemic and cross-reactive mucosal antibody responses in human volunteers, reported researchers...Systemic and cross-reactive mucosal antibody responses in human volunteers," Journal of...patients who demonstrated high nasal antibody responses also developed increased serum IgA...
- Induction of Antibody Responses to New B-Cell Epitopes Indicates Vaccination...
- Newspaper article from: Immunotherapy Weekly August 9, 1999 700+ words
...Valenta, R. "Induction of Antibody Responses to New B-Cell Epitopes Indicates...Immunology, "Whether the modulation of antibody responses can contribute to the improvement...in allergen/epitope-specific antibody responses: increases in IgG subclass (IgG1...
