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Stability indicating method for SPf66 antimalarial peptide in solution.

Vaccine Weekly

| July 07, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JUL 7 - (NewsRx.com & NewsRx.net) -- Scientists have developed a method for indicating the stability of SPf66 antimalarial peptide in solution.

According to published research from Spain, "Stability studies on the SPf66 antimalarial peptide with different PH and temperature conditions were carried out. The degradation mechanism was elucidated by the size-exclusion chromatography (SEC) technique and the experimental data obtained at 37 degrees C and different pH were fitted to a kinetic degradation model that could explain the loss of its immunogenic capacity."

"At 5, 25, 37, and 70 degrees C and pH 2, changes were detected in the areas of the different species, although the values obtained could not be fitted to any known degradation kinetics," reported Ana Santovena and colleagues at the Universidad de La Laguna.

Santovena and colleagues ...

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Source: HighBeam Research, Stability indicating method for SPf66 antimalarial peptide in...

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