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Report Challenges Blood Stem-Cell Role in Rebuilding Heart.

The Boston Globe (Boston, MA)

| March 22, 2004 | This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

Byline: Gareth Cook

Mar. 22--One of the most spectacular biomedical findings of the past few years was called into question yesterday when scientists published evidence that they had failed to get stem cells in the blood to rebuild the heart.

The work, reported in the prestigious journal Nature, appears to undermine a landmark 2001 study that gave many doctors and patients hope that medicine could overcome one of the nation's leading killers by finding a way to repair damaged heart tissue.

The new report is also politically charged, since it undercuts a key premise of the Bush administration's limits on embryonic stem cell research. The Bush policy was built partly in the belief that adult stem cells, such as those used in the study, are almost as flexible as the more controversial embryonic cells. But the new findings are part of a wave of new, more rigorous research showing that many of those early claims for adult stem cells were wrong.

"These papers are both very definitive,…

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