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Autotransplantation of ovarian tissue recommended for trials only.

Women's Health Weekly

| July 01, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JUL 1 - (NewsRx.com & NewsRx.net) -- Researchers report that further studies are needed before the reimplantation of cortical tissue is considered a valid option in fertility treatment.

J. Radford and colleagues, Christie Hospital NHS Trust, U.K., explained, "Temporary ovarian function has been reported following reimplantation of frozen/thawed cortical tissue and it is hoped that in time this technique will allow women sterilized by treatment for cancer to regain their fertility."

Evidence shown in animal studies raised questions, though. "There is, however, a concern, supported by animal data, that ovarian tissue may be contaminated by disease capable of causing a relapse after transplantation. One experiment in which ovarian tissue from women with lymphoma was xenografted into immunodeficient mice showed no evidence of transmission but these results require confirmation and no data exists for other malignancies," Radford and coauthors said.

"For the time being, therefore, it is recommended that harvesting and reimplantation of ovarian ...

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