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Mammography technique reveals more hemoglobin in tumors than healthy tissue.

Women's Health Weekly

| July 01, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JUL 1 - (NewsRx.com & NewsRx.net) -- Using time-domain optical mammography, researchers in Germany found higher hemoglobin concentrations and blood oxygen saturation in breast cancer tumors than in healthy tissue.

D. Grosenick and colleagues reported: "Using a dual-wavelength (670 nm, 785 nm) time-domain scanning instrument we have recorded optical mammograms of 93 patients suspected of having breast cancer, which was subsequently assessed histologically.

"Among 65 histologically confirmed carcinomas, 54 were detectable in at least one of two optical mammograms recorded of each tumor-bearing breast in craniocaudal and mediolateral projection. Optical mammograms were based on photon counts in selected time windows of measured distributions of times of flight of photons," the researchers said.

"Optical properties of 50 carcinomas investigated at both wavelengths were derived by modeling the breast as partially homogeneous infinite slab with an embedded spherical inhomogeneity representing the tumor and by calculating the diffraction of photon density waves. In selected cases, additional information about the location of the tumor along the compression direction was used that was obtained from scans at ...

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