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Provigil.(New and Approved)(wakefulness-promoting agent)

Family Practice News

| May 15, 2004 | Mechcatie, Elizabeth | COPYRIGHT 2009 International Medical News Group. (Hide copyright information)Copyright

(modafinil, Cephalon)

A "wakefulness-promoting agent" approved to improve wakefulness in patients with excessive sleepiness associated with obstructive sleep apnea/hypopnea syndrome (OSA/HS) and shaft work sleep disorder (SWSD). First approved in 1998 for improving wakefulness in narcolepsy.

* Recommended Dosage: 200 mg once a day, in the morning (for OSA/HS) or an hour before starting work shift (for SWSD).

* Special Considerations: Main side effects are headache, dizziness, nausea, and suppression of appetite initially, Starting at a lower dose (100 mg) and gradually increasing it over the first week helps minimize these effects, according to Dr. …

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