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Live genetically modified bacteria may act as drug delivery tools.

Drug Week

| June 11, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JUN 11 - (NewsRx.com & NewsRx.net) -- Live genetically modified bacteria may act as drug delivery tools.

According to published research from Ireland, "Recent advances in genetic modification technology show that lactic acid bacteria can constitutively produce functional, eukaryote-derived proteins without any apparent negative effect on bacterial growth and physiology. These bacteria appear capable of surviving and of being physiologically active at the mucosal surfaces of higher eukaryotes. Studies in animal models also suggest that-these findings could have a major impact in human medicine."

"Alongside conceptual proofs, the development of a robust system for biological containment will allow for the examination of genetically modified lactic acid bacteria as vectors of therapeutic protein delivery in human healthcare," wrote Lothar Steidler at University College Cork.

Steidler published the report in ...

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