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Increased islet mass is linked to decreased islet blood flow during pregnancy.
2004 JUN 3 - (NewsRx.com & NewsRx.net) -- Increased islet mass is linked to decreased islet blood flow during pregnancy.
"Increased blood perfusion of pancreatic islets is seen during various conditions of increased demand for insulin secretion. Pregnancy confers an increased need for insulin secretion, met by increased islet mass and volume as well as a decreased threshold for glucose-induced insulin secretion. In the present study, whole pancreatic and islet blood flow were studied with a microsphere technique in Wistar rats on days 15, 18 and 20 of pregnancy and days 2 and 7 postpartum," scientists in Sweden report.
"There were no changes in total pancreatic blood flow during pregnancy and the first postpartum week. Total blood perfusion through islet tissue expressed as flow per weight of whole pancreas was higher at day 15 of pregnancy. When islet blood flow was expressed per grain of islet tissue there was a decrease at day 18 of pregnancy," noted A.M. Svensson and colleagues, Biomedical Center, Department of Medical Cell Biology.
"This decrease of islet blood flow was concomitant to a short-lived increase of the islet mass at the end of pregnancy. We ...
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- Increased islet mass is linked to decreased islet blood flow during pregnancy.
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Source: HighBeam Research, Increased islet mass is linked to decreased islet blood flow during...