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Gefitinib and trastuzumab show promise for treatment of metastatic breast cancer.
2004 JUN 3 - (NewsRx.com & NewsRx.net) -- The combination of gefitinib and trastuzumab shows promise for the treatment of metastatic breast cancer (MBC).
"Despite new therapies and several treatment options," MBC "remains incurable," oncologists in Germany explained. "One reason for the low median survival rate may be intense cross-talk between growth factor receptors such as the epidermal growth factor receptor (EGFR/HER1) and the HER2 growth factor receptor."
A. Schneeweiss and colleagues at the University of Heidelberg described "the case history of a patient with MBC whose disease had progressed despite surgery, radiotherapy and four different chemotherapy regimens, including trastuzumab (a monoclonal antibody that specifically blocks HER2) combined with docetaxel.
"However, treatment with 500 mg/day gefitinib ('Iressa', ZD1839), an EGFR tyrosine kinase inhibitor, and trastuzumab (2 mg/kg/week) caused a rapid and sustained regression of breast cancer metastases in skin and lymph nodes," according to the report.
"Thus, for patients with MBC whose tumors ...
- TAIHO PHARMACEUTICAL HIGHLIGHTING BREAST CANCER DRUGS.
- News wire article from: AsiaPulse News December 6, 2004 700+ words
...and marketing of drugs for breast cancer. Cancer drugs are a major earner for Taiho...But with incidences of breast cancer on the rise, the company...to give more attention to breast cancer treatments. Clinical trials...
- UC Davis researchers identify a protein that may help breast cancer spread,...
- Newspaper article from: Blood Weekly April 16, 2009 700+ words
...the essential ingredient that allows breast cancer to spread to other organs and resist...was not always expressed in primary breast cancer tumors, yet it could be present in...function in the process of metastasis. "Breast cancer deaths are caused by metastasis, not...
- Research and Markets: Keep Up-to-Date on the Progress of the Most Pronounced...
- Press release article from: Business Wire June 24, 2005 700+ words
...to late stage drugs with breast cancer therapy strategies. This...most pronounced anti-cancer drugs in development for breast cancer treatment. We also view...made for the top ranking breast cancer drugs. An analyzes that provide...
- National Breast Cancer Advocate Provides Personal Viewpoint About Recent News...
- Press release article from: PR Newswire September 2, 1998 700+ words
...Women on the Front Lines Battling Breast Cancer DALLAS, Sept. 2 /PRNewswire...FDA committee is reviewing two breast cancer drugs, Herceptin and Tamoxifen. No...bound to have questions. As a breast cancer survivor and founding chairman...
- BREAST CANCER DRUGS PRESENT DIFFICULT CHOICE.(News/National/International)
- Newspaper article from: Rocky Mountain News (Denver, CO) September 3, 1998 700+ words
...approval of two very different breast cancer drugs Wednesday. Information on which...Tamoxifen, now sold to treat breast cancer, also could help certain healthy...reduce their risk of getting breast cancer later in life, the FDA panel...
- Vital breast cancer drugs highlight funding ethics.(Izindaba)
- Magazine article from: South African Medical Journal Bateman, Chris November 1, 2008 700+ words
...ongoing reluctance to proclaim two breast cancer drugs proven to slow early disease...Registry, 1999) put annual breast cancer diagnoses in South Africa at...treats about 350 new cases of breast cancer a year, said texanes increased...
- Breast Cancer Drugs Typically Used In Later Stages Of The Disease Find A Market...
- Press release article from: PR Newswire July 9, 2002 700+ words
...issues, announced today that breast cancer drugs typically used in later stages...well. The report, entitled Breast Cancer, also found that tamoxifen...the treatment of early stage breast cancer," said Sarah Simnett, analyst...
- Watchdog gives green light to new breast cancer drugs.(News)
- Newspaper article from: Birmingham Mail (England) August 11, 2006 700+ words
BREAST cancer drugs hailed as a breakthrough in treatment...in postmenopausal women with early breast cancer. The drugs reduce the risk of tumours...with hormone receptor positive early breast cancer. They are Arimidex, Femara and Aromasin...
