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Aromatase inhibitors for postmenopausal breast cancer therapy reviewed.
2004 JUN 3 - (NewsRx.com & NewsRx.net) -- Researchers review aromatase inhibitors for the treatment of postmenopausal breast cancer in a recent issue of the Journal of the American Geriatrics Society.
"This article provides a comprehensive review of aromatase inhibitors (AIs) for geriatricians, because it appears that more elderly women will be using these drugs in the near future.
Computerized literature searches of Medline were conducted through May 2003. Key words/phrases included in the literature searches were aromatase inhibitors, estrogen, and breast cancer. Limits included English language, age 65 and older, and female sex. All relevant articles were selected and reviewed," scientists in the United States report.
"AIs suppress intratumoral and plasma estrogen levels significantly," said Amit Arora and Jane F. Potter at the University of Nebraska. "Third-generation AIs have excellent pharmacological profiles, with no significant drug interactions and better tolerability. These drugs have shown superiority compared with conventional therapies. The results of anastrozole, tamoxifen, and combination trials favors anastrozole over tamoxifen for adjuvant treatment, but further follow-up is required. AIs are approved for the treatment of advanced metastatic breast cancer (BC) in ...
- Exemestane and aromatase inhibitors play role in breast cancer management.
- Newspaper article from: Vaccine Weekly April 21, 2004 700+ words
...Exemestane and aromatase inhibitors play a role...advanced breast cancer. "In metastatic...advanced breast cancer, aromatase inhibitors and inactivators...Exemestane and aromatase inhibitors in the management...advanced breast cancer. ...
- Aromatase inhibitors in breast cancer assessed by ASCO Committee.(American...
- Magazine article from: Women's Health Weekly June 20, 2002 700+ words
...the use of aromatase inhibitors in the treatment...women with breast cancer has generated...the use of aromatase inhibitors. Specific to the adjuvant breast cancer setting...advanced breast cancer setting, data on aromatase inhibitors have ...
- Aromatase Inhibitors Declared Superior to Tamoxifen in the Adjuvant Treatment...
- Press release article from: PR Newswire August 1, 2006 700+ words
...panel of breast cancer specialists...value of aromatase inhibitors such as ARIMIDEX...of leading breast cancer specialists...agreed that aromatase inhibitors (AIs) surpass...the use of aromatase inhibitors in early breast cancer, and while...
- Aromatase inhibitors improve breast cancer survival.(cancer treatments)(Brief...
- Magazine article from: Focus on Healthy Aging December 1, 2006 700+ words
Score another win for the class of breast cancer drugs known as the aromatase inhibitors. A study in the September 20 Journal of...significantly improve survival in women with advanced breast cancer compared with the standard drug, tamoxifen...
- New breast cancer drug.(aromatase inhibitors)(Brief Article)
- Magazine article from: U.S. News & World Report Brink, Susan December 24, 2001 700+ words
...menopausal women with breast cancer more than tamoxifen...new drugs, called aromatase inhibitors, block fat cells...fuels the growth of breast cancer cells. But this...with early-stage breast cancer who took one of the...
- Watch for poor bone health after breast cancer.(Women's Health)(Aromatase...
- Magazine article from: Internal Medicine News Palkhivala, Alison October 15, 2007 700+ words
...MONTREAL -- Aromatase inhibitors can wreak...treated for breast cancer, Dr. Eugene...chemotherapy for breast cancer has been associated...closely by aromatase inhibitors (AIs...for early breast cancer, replacing...
- Endocrine-responsive breast cancer in the elderly: role of aromatase...
- Magazine article from: Advances in Oncology Aapro, Matti March 1, 2009 700+ words
...including aromatase inhibitors, is important...patients with breast cancer who frequently...the data on aromatase inhibitors, including...sensitive breast cancer, whether...trials of the aromatase inhibitors, evidence...
- Genomic Health Announces Study Establishing the Utility of Oncotype DX(R) in...
- Press release article from: PR Newswire December 13, 2008 700+ words
...early stage breast cancer. In this...wide use of aromatase inhibitors for adjuvant...positive breast cancer. "Our multivariate...treated with aromatase inhibitors. In addition...Oncotype DX breast cancer assay by studying...