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Third-generation vaccine against smallpox tested.

Vaccine Weekly

| June 02, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 JUN 2 - (NewsRx.com & NewsRx.net) -- Not everybody can safely be vaccinated against smallpox using the current U.S. Food and Drug Administration-approved vaccine.

Scientists hope another study vaccine, now undergoing its first testing in the U.S. at St. Louis University, will give a choice to people who can't be given the current vaccine, known as Dryvax.

"There are limits to the current vaccine," said Sharon Frey, MD, from St. Louis University's Center for Vaccine Development. "You can't give Dryvax to people with certain skin conditions, such as eczema, or to people who are immunosuppressed. So, for example, if you are HIV-positive or undergoing chemotherapy for cancer, you shouldn't receive the currently licensed vaccine."

Frey said this study vaccine, known as MVA-BN and provided through Bavarian Nordic, is different than other vaccines that are now available. Like the current vaccines, the study vaccine is a live-virus vaccine made from vaccinia virus, but this study vaccine contains a much more attenuated form of the virus.

"The thinking is that the study vaccine is ...

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Source: HighBeam Research, Third-generation vaccine against smallpox tested.

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