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Passive transfer of antibody prevents SARS replication.
2004 JUN 2 - (NewsRx.com & NewsRx.net) -- Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice.
According to a study from the United States, "Following intranasal administration, the severe acute respiratory syndrome (SARS) coronavirus replicated to high titers in the respiratory tracts of BALB/c mice. Peak replication was seen in the absence of disease on day 1 or 2, depending on the dose administered, and the virus was cleared within a week. Viral antigen and nucleic acid were detected in bronchiolar epithelial cells during peak viral replication.
"Mice developed a neutralizing antibody response and were protected from re-infection 28 days following primary infection," reported Kanta Subbarao and collaborators at the National Institutes of Health and the Centers for Disease Control and Prevention. "Passive transfer of immune serum to naive mice prevented virus replication in the lower respiratory tract following intranasal challenge. Thus, antibodies, acting alone, can prevent replication of the SARS coronavirus in the lung, a ...
- Passive transfer of antibody prevents SARS replication.
- Newspaper article from: Vaccine Weekly May 19, 2004 700+ words
...Prior infection and passive transfer of neutralizing antibody...and Prevention. "Passive transfer of immune serum to...Prior infection and passive transfer of neutralizing antibody...article was prepared by Vaccine Weekly editors from staff...
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- Newspaper article from: Vaccine Weekly February 25, 2004 700+ words
...subscript]42) as well as passive transfer of anti-A-beta antibodies...This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2004, Vaccine Weekly via NewsRx.com & NewsRx...
- Stat 4-mediated immune mechanisms essential in protection against plague.
- Newspaper article from: Vaccine Weekly December 29, 2004 700+ words
...could not be overcome even by the passive transfer of CD4+ cells from immunized...This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2004, Vaccine Weekly via NewsRx.com & NewsRx...
- IgG antibodies confer sterilizing protection to SHIV-infected macaques.
- Newspaper article from: Vaccine Weekly February 4, 2004 700+ words
...study from the United States, "Passive transfer of high-titered antiviral neutralizing...This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2004, Vaccine Weekly via NewsRx.com & NewsRx...
- SARS coronavirus spike protein protectively immunizes mice.
- Newspaper article from: Vaccine Weekly July 7, 2004 700+ words
...reported the researchers. "Passive transfer of serum from mice immunized with...This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2004, Vaccine Weekly via NewsRx.com & NewsRx...
- Glycoconjugate vaccine for Neisseria meningitidis is protective in rats.(Brief...
- Newspaper article from: Vaccine Weekly January 22, 2003 700+ words
...to reduce bacteremia after passive transfer into a neonate rat model...9960) was observed." Via passive transfer to neonate rats, Mountzouros...This article was prepared by Vaccine Weekly editors from staff and other...
- Novel gene therapy approach suppresses autoimmune encephalomyelitis.
- Newspaper article from: Vaccine Weekly July 7, 2004 700+ words
...MBP). With this treatment, passive transfer of clinical EAE can be blocked...This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2004, Vaccine Weekly via NewsRx.com & NewsRx...
- Hepatitis B surface antigenemia occurs after hepatitis A and B vaccination.
- Newspaper article from: Vaccine Weekly March 31, 2004 700+ words
...available assays. It is caused by a passive transfer of antigen by vaccination, and...This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2004, Vaccine Weekly via NewsRx.com & NewsRx...
Source: HighBeam Research, Passive transfer of antibody prevents SARS replication.