AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Peptide-based vaccine effective for prostate cancer.
2004 JUN 2 - (NewsRx.com & NewsRx.net) -- A synthetic luteinizing hormone releasing hormone (LHRH) vaccine was effective for the treatment of prostate cancer.
"We have designed a peptide-based immunotherapeutic vaccine for treatment of androgen-responsive prostate cancer. The vaccine targets the luteinizing hormone-releasing hormone (LHRH) decapeptide that results in an androgen-deprivation immunotherapy. The design elements of the peptide immunogens are the LHRH peptide or B cell epitope synthetically linked to different promiscuous helper T cell (Th) sequences, the UBITh epitopes, derived from four natural pathogens for effective immunogenicity in outbred populations, and in some cases, also linked to an adjuvanting peptide from Yersinia invasin (Inv) protein," scientists writing in the journal Vaccine report.
"The UBITh LHRH immunogens are adsorbed on Alhydrogel or formulated as several different oil-based emulsions and tested in rodents, dogs, and a non-human primate, baboons," said Connie L. Finstad and collaborators at United Biomedical Inc., New York University School of Medicine, and the Southwest Foundation for Biomedical Research.
"The immunogens generate an anti-LHRH antibody response specific to the LHRH decapeptide element in contrast to LHRH conjugate-carrier protein vaccines where only a small portion of the antibody response is directed to the target epitope and epitopic suppression is noted," ...
- Androgen deprivation affects thyroid function tests in prostate cancer.
- Newspaper article from: Vaccine Weekly June 23, 2004 700+ words
...hormonally treated prostate cancer." Salminen and...function tests in prostate cancer patients. Anti...subject areas of Prostate Cancer, Endocrinology...article was prepared by Vaccine Weekly editors from staff...
- Therapy for rising PSA after prostate cancer treatment reviewed.
- Newspaper article from: Vaccine Weekly June 9, 2004 700+ words
...primary treatment for prostate cancer. According to a...primary treatment for prostate cancer. Urology, 2003...subject areas of Prostate Cancer Therapy, Endocrinology...article was prepared by Vaccine Weekly editors from staff...
- Tumor-associated antigens show promise for prostate cancer vaccines.
- Newspaper article from: Vaccine Weekly July 7, 2004 700+ words
...testis antigens expressed in prostate cancer using cDNA phage surface...the major subject areas of Prostate Cancer Vaccine, Prostate Cancer, Cancer Vaccine, Immunology...article was prepared by Vaccine Weekly editors from staff and other...
- Salvage radiotherapy for treatment of prostate cancer reviewed.
- Newspaper article from: Vaccine Weekly June 9, 2004 700+ words
...the treatment of prostate cancer in a recent issue...the treatment of prostate cancer. Urology, 2003...subject areas of Prostate Cancer, Metastatic Disease...article was prepared by Vaccine Weekly editors from staff...
- Peptide vaccine helpful for HLA-A2-positive patients with prostate cancer.
- Newspaper article from: Vaccine Weekly March 31, 2004 700+ words
...hormone-refractory prostate cancer patients," concluded...hormone-refractory prostate cancer. Cancer Sci, 2004...subject areas of Prostate Cancer, Cancer Vaccine...article was prepared by Vaccine Weekly editors from staff...
- Vaccine benefits some prostate cancer patients in biochemical relapse.
- Newspaper article from: Vaccine Weekly July 7, 2004 700+ words
...Vaccination of prostatectomized prostate cancer patients in biochemical...the major subject areas of Prostate Cancer Vaccine, Prostate Cancer, Cancer Vaccine, Dendritic...article was prepared by Vaccine Weekly editors from staff and other...
- Dendritic cell vaccine for prostate cancer immunotherapy possible.
- Newspaper article from: Vaccine Weekly June 9, 2004 700+ words
...cancer immunotherapy. Prostate Cancer Prostatic Dis, 2004...information for the journal Prostate Cancer and Prostatic Diseases...subject areas of Prostate Cancer Therapy, Cancer...article was prepared by Vaccine Weekly editors from staff...
- Prostate cancer vaccine on track for phase III clinical trials.
- Newspaper article from: Vaccine Weekly November 27, 2002 700+ words
...lead program, GVAX prostate cancer vaccine, which is...are under way in prostate cancer, lung cancer, pancreatic...CG7060 and CG7870 in prostate cancer. Preclinical stage...article was prepared by Vaccine Weekly editors from staff...
- Rights regained to ex vivo prostate cancer immunotherapy.(Brief Article)
- Newspaper article from: Vaccine Weekly January 22, 2003 700+ words
...immunotherapy products for prostate cancer that are produced...clinical response in prostate cancer patients treated...abundantly expressed on prostate cancer cells and therefore...article was prepared by Vaccine Weekly editors from staff...
- Black men should be screened for prostate cancer at younger age.
- Newspaper article from: Vaccine Weekly January 7, 2004 700+ words
...early detection of prostate cancer to include the following...men diagnosed with prostate cancer in the prostate...519 patients with prostate cancer initially seen...article was prepared by Vaccine Weekly editors from staff...
Source: HighBeam Research, Peptide-based vaccine effective for prostate cancer.