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Systemic treatment of esophageal cancer reviewed.
2004 JUN 2 - (NewsRx.com & NewsRx.net) -- Scientists review systemic treatment of esophageal cancer in a recent issue of the European Journal of Gastroenterology and Hepatology.
"Most patients with esophageal cancer present with locally advanced or metastatic disease. In an effort to improve the results of surgery in patients with operable disease, strategies to incorporate radiotherapy and chemotherapy, preoperatively (neoadjuvant) and postoperatively (adjuvant), have been extensively investigated in numerous clinical trials. Meta-analyses of neoadjuvant trials did not demonstrate a survival advantage for neoadjuvant chemotherapy or concurrent chemoradiotherapy," investigators in the Netherlands report.
"Although local control seems to be improved with neoadjuvant treatment, the currently used chemotherapeutic agents are simply not effective enough to eradicate micro-metastatic disease," said Dirk J. Richel and Walter L. Vervenne at Academy Medical Center in Amsterdam. "Patients who undergo neoadjuvant treatment and achieve a histologically confirmed complete response have a significant better survival than those who do not achieve such a response. Although neoadjuvant chemoradiotherapy is able to induce a higher rate of complete pathological responses compared to neoadjuvant chemotherapy (25-30% vs 5-15%), this advantage is counteracted by a higher incidence of ...
- Systemic treatment of esophageal cancer reviewed.
- Newspaper article from: Cancer Weekly May 18, 2004 700+ words
...treatment of esophageal cancer in a recent issue of the European Journal of Gastroenterology...patients with esophageal cancer present with...treatment of esophageal cancer has to be...study in the European Journal of Gastroenterology...
- Gene variations alter risk of esophageal cancer.
- Newspaper article from: Clinical Oncology Week November 17, 2008 700+ words
...a common gene pathway may affect esophageal cancer risk, a dangerous and rapidly increasing...related to microRNAs (miRNAs) and esophageal cancer, are published in the November issue...of miRNA-related genes influence esophageal cancer has largely remained unknown...
- Genetic predictors of esophageal cancer identified.
- Newspaper article from: Obesity & Diabetes Week November 17, 2008 700+ words
...identified 11 genotypes that may increase esophageal cancer risk, according to research published...a significantly increased risk of esophageal cancer with increasing numbers of risk genotypes...Cancer Center. Major risk factors for esophageal cancer include obesity, smoking and ...
- Esophageal cancer.(Disease/Disorder overview)
- CareNotes February 1, 2007 700+ words
GENERAL INFORMATION: What is esophageal cancer? Esophageal cancer is a tumor of the tube connecting the mouth to...parts of the body (metastasis). What causes esophageal cancer? There is no known cause of esophageal cancer...
- Esophageal cancer.
- CareNotes May 1, 2007 700+ words
GENERAL INFORMATION: What is esophageal cancer? Esophageal cancer is a tumor of the tube connecting the mouth to...parts of the body (metastasis). What causes esophageal cancer? There is no known cause of esophageal cancer...
- Esophageal Cancer: An Overview.
- Magazine article from: MedSurg Nursing Brooks-Brunn, Jo Ann October 1, 2000 700+ words
...an estimated 12,500 new cases of esophageal cancer in the United States (9,400 males...projected new cases and deaths from esophageal cancer (see Figure 1) (American Cancer...Figure 1 ILLUSTRATION OMITTED] Esophageal cancer has the greatest variation in geographic...
- Mayo Clinic Studies Find Association Between Acid Reflux and Esophageal Cancer,...
- News wire article from: Europe Intelligence Wire May 23, 2006 700+ words
...basis for Barrett's esophagus and esophageal cancer (adenocarcinoma). These studies...authors of one study, the incidence of esophageal cancer is increasing at what has been called...a significant association between esophageal cancer and gastroesophageal reflux disease...
- Segregation analysis of esophageal cancer in 221 high-risk Chinese families....
- Newspaper article from: Cancer Weekly June 1, 1992 700+ words
...to predispose certain families to esophageal cancer, according to a segregation analysis...considered the greatest risk factors for esophageal cancer, but recent studies suggest that...revealed striking similarities in the esophageal cancer death rates for blood relatives and...
- Access to care and stage at diagnosis for patients with lung cancer and...
- Magazine article from: Southern Medical Journal Silverstein, Marc D. Nietert, Paul J. Ye, Xiaobu Lackland, Daniel T. August 1, 2002 700+ words
...Methods. All cases of lung and esophageal cancer between 1991 and 1995 in the Savannah...a predictor of advanced stage in esophageal cancer patients. Conclusions. In this...there would be 13,200 new cases of esophageal cancer in the United States in 2001, and...
- UK researchers develop test to detect esophageal cancer.
- Newspaper article from: Diagnostics & Imaging Week Kingman, Sharon August 19, 2004 700+ words
...A new and simple test for esophageal cancer could be in general use within...results show that we can detect esophageal cancer with the same accuracy in...implications for people with esophageal cancer are particularly important...
Source: HighBeam Research, Systemic treatment of esophageal cancer reviewed.