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Hamster model for Chlamydia pneumoniae infection developed.
2004 JUN 2 - (NewsRx.com & NewsRx.net) -- Scientists have developed a hamster model for Chlamydia pneumoniae infection.
"We report that intraperitoneal injection of Chlamydia pneumoniae purified elementary bodies (EBs) in the hamster causes a systemic infection allowing the isolation of viable chlamydiae from several organs for several days post-infection (p.i.). In particular, spleen infection occurred up to day 7 p.i. in 100% of animals," researchers in Italy report.
"Systemic infection probably occurs via macrophages as intraperitoneally injected chlamydiae which are taken up by the hamster macrophages remain viable and can infect in vitro cell cultures," said Vittorio Sambri and collaborators at the University of Bologna and Chiron Vaccines. "Immunization of 18 hamsters with heat-in activated purified EBs, completely protected the spleens of 16 animals and substantially reduced infection levels in the remaining two.
"This model, therefore, provides a robust screening tool for the assessment of the protective activity of potential vaccine candidates," stated the investigators. "In a pilot study on five recombinant antigens recently described as ...
- Hamster model for Chlamydia pneumoniae infection developed.
- Newspaper article from: Vaccine Weekly May 19, 2004 700+ words
...hamster model for Chlamydia pneumoniae infection...intraperitoneal injection of Chlamydia pneumoniae purified elementary...Experimental infection by Chlamydia pneumoniae in the hamster...was prepared by Vaccine Weekly editors from staff...
- Chlamydia pneumoniae infection is unrelated to squamous cell carcinoma.
- Newspaper article from: Obesity, Fitness & Wellness Week July 24, 2004 700+ words
...com & NewsRx.net) -- Chlamydia pneumoniae infection appears to be unrelated...epidemiological data, an association between Chlamydia pneumoniae (Cp) infection and head and neck...Anticancer Research (Prevalence of Chlamydia pneumoniae infection in squamous cell carcinoma...
- Fight germs, fight heart disease?(Chlamydia pneumoniae)(Brief Article)
- Magazine article from: U.S. News & World Report Brink, Susan March 13, 2000 700+ words
...specifically with a bug called Chlamydia pneumoniae. If true, the idea could radically...the journal Lancet showing that Chlamydia pneumoniae was often found in the artery...causes atherosclerosis. "[Chlamydia pneumoniae] may be an innocent bystander...
- Uracil-DNA glycosylase of Chlamydia pneumoniae characterized.
- Magazine article from: Women's Health Weekly June 17, 2004 700+ words
...characterized uracil-DNA glycosylase of Chlamydia pneumoniae. According to a study from China...glycosylase gene was cloned from Chlamydia pneumoniae AR39 and expressed in E. coli strains...characterization of uracil-DNA glycosylase of Chlamydia pneumoniae in Escherichia coli. ...
- Chlamydia Pneumoniae May Contribute to Heart Attacks, Strokes.
- News wire article from: Ascribe Higher Education News Service December 3, 2002 700+ words
...Newswire) -- Analysis of available data suggests that Chlamydia pneumoniae, which causes "walking pneumonia," may contribute...abstracts and expert opinion for the association between Chlamydia pneumoniae (C pneumoniae) and atherosclerosis. They included...
- Chlamydia pneumoniae may be an infectious risk factor for atherosclerosis.
- Newspaper article from: Cardiovascular Week July 19, 2004 700+ words
...the accumulating evidence that chronic infection with Chlamydia pneumoniae, a ubiquitous human respiratory pathogen, might contribute...published their study in Nature Reviews Microbiology (Chlamydia pneumoniae:An infectious risk factor for atherosclerosis? Nat...
- Microbe linked to Alzheimer's disease.(Chlamydia pneumoniae)(Brief Article)
- Magazine article from: Science News Travis, John November 21, 1998 700+ words
Chlamydia pneumoniae is getting a bad reputation. Scientists first identified the bacterium a decade ago...people enfeebled by late-stage Alzheimer's. "They may just be more susceptible to Chlamydia pneumoniae," he says.
- Chlamydia pneumoniae infection in a breeding colony of African clawed frogs...
- Magazine article from: Emerging Infectious Diseases Reed, Kurt D. Ruth, George R. Meyer, Jeanine A. Shukla, Sanjay K. March 1, 2000 700+ words
...chlamydiosis. Chlamydial inclusions were observed by light and electron microscopy in the liver of an infected frog. Chlamydia pneumoniae was isolated in cell cultures from four frogs. A cutaneous infection by a chytridiomycete fungus observed in...
