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IL-15 may be beneficial for AIDS immunotherapy.
2004 JUN 2 - (NewsRx.com & NewsRx.net) -- Interleukin-15 (IL-15) may be beneficial for AIDS immunotherapy.
According to recent research published in the journal Trends in Immunology, "The current antiretroviral therapy has improved the clinical outcome of HIV-infected patients. However, the drug toxicity, the emergence of drug-resistant HIV variants and the incomplete reconstitution of immune responses underline the need for additional therapeutic strategies, such as cytokine-based therapy. Interleukin-15 (IL-15) has a central role in the immune response during HIV infection.
"Recently, defective production of IL-15 has been found in AIDS patients and it might account for the impairment of natural and adaptive immune responses against HIV," said Claudio M. Mastroianni and colleagues at La Sapienza University. "IL-15 is more potent than IL-2 and IL-7 in enhancing the function of HIV-specific CD8+ T cells and it is a superior HIV vaccine molecular adjuvant. In this ...
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Source: HighBeam Research, IL-15 may be beneficial for AIDS immunotherapy.