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Ultraviolet-A triggers signals linked to skin tumor promotion and progression.
2004 MAY 14 - (NewsRx.com & NewsRx.net) -- Ultraviolet-A triggers signals linked to skin tumor promotion and progression.
According to a study from the United States, "each year more than 1,000,000 cases of non-melanoma skin cancer (NMSC) are diagnosed in the United States. Solar radiation has been described as an important etiological factor in the development of NMSC. UVA comprises the largest portion of solar radiation reaching the surface of the earth (90-99%) and has been described to lead to benign tumor formation as well as malignant cancers, squamous cell carcinomas (SCCs).
"While much research has focused upon the effects of UVB radiation, little is known about UVA-induced signaling pathways and their role in tumor promotion. Here we focus on UVA-mediated activation of mitogen-activated protein kinase (MAPK) pathways and their role in activator protein-1 (AP-1) mediated transcription and cyclooxygenase-2 (COX-2) expression," M.A. Bachelor and colleagues, University Arizona, College of Medicine reported.
"AP-1 and COX-2 have been found to play a role in angiogenesis in other tissues. We propose UVA-mediated increases in AP-1 and COX-2 may play a role in tumor promotion through ...
- Stat3 activation may be a critical event during skin tumor promotion.
- Newspaper article from: Cancer Weekly June 15, 2004 700+ words
...be a critical event during skin tumor promotion. "In the present study...particularly Stat3, in mouse skin tumor promotion and multistage carcinogenesis...critical event during mouse skin tumor promotion, possibly through regulation...
- Ultraviolet-A triggers signals linked to skin tumor promotion and progression.
- Newspaper article from: Biotech Week May 12, 2004 700+ words
...triggers signals linked to skin tumor promotion and progression. According...COX-2 may play a role in tumor promotion through increases in interleukin...signaling pathways involved in skin tumor promotion and progression. Semin Cancer...
- Inhibition of tumor promotion in murine skin by green tea polyphenols....
- Newspaper article from: Cancer Weekly Katiyar, Santosh K. Agarwal, Rajesh Mukhtar, Hasan July 20, 1992 700+ words
...chemopreventive effects in murine skin tumor bioassay systems (Carcinogenesis...decarboxylase (ODC) activity and on skin tumor promotion was assessed. Prior application...various structurally different skin tumor promoters. Among various epicatechin...
- Zerumbone suppresses skin tumor initiation and promotion stages in ICR mice.
- Newspaper article from: Cancer Weekly July 27, 2004 700+ words
...Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice, and looks promising...Zerumbone, a sesquiterpene in subtropical ginger, suppresses skin tumor initiation and promotion stages in ICR mice. Int J Cancer...
- Gene courier targets skin-tumor cells. (liposomes used to carry therapeutic...
- Magazine article from: Science News Fackelmann, Kathy A. December 4, 1993 700+ words
...positive response, Nabel's team reports in the Dec. 1 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. In that case, a skin tumor that had been injected directly with the experimental mixture completely disappeared, as did several other tumors that were...
- Noninvasive imaging beneficial for skin tumor diagnosis and treatment efficacy.
- Newspaper article from: Biotech Week May 19, 2004 700+ words
2004 MAY 19 - (NewsRx.com & NewsRx.net) -- Noninvasive imaging is beneficial for skin tumor diagnosis and treatment efficacy. Different "approaches to the diagnosis of skin tumors using noninvasive diagnostic tools which...
- Photoelectron Corporation Announces Start of Skin Tumor Trials
- Press release article from: PR Newswire July 30, 1998 700+ words
...Radiosurgery System (PRS), a proprietary x-ray delivery system for tumor therapy, announced today the commencement of skin tumor trials at Our Lady of Mercy Medical Center, a University Hospital of New York Medical College in New York. Dr. Basil Hilaris...
- Rare skin tumor responds better to treatment than melanoma.
- Newspaper article from: Clinical Oncology Week February 16, 2009 700+ words
University of Michigan Health System researchers have published new data to help answer two dreaded questions: "Is it cancer?" and "What type of treatment should I have?" Cancer is the primary concern when abnormal skin lesions are detected. Macroscopic and microscopic features of a lesion usually
- Modulation of N-nitrosomethylurea-induced mammary tumor promotion by dietary...
- Newspaper article from: Cancer Weekly April 8, 1991 700+ words
SOURCE: Journal of the National Cancer Institute, April 3, 1991;83(7):496-501. Dietary fiber may counteract the apparent breast cancer-promoting effect of dietary fat, according to a murine study conducted by New York researchers. Multiple studies suggest a strong causal relationship between
- Triterpenoids.(Cosmeceutical Critique)
- Magazine article from: Skin & Allergy News Bauman, Leslie S. June 1, 2008 700+ words
...F, also displayed significant activity against skin tumor promotion in an in vivo two-stage murine carcinogenesis...to demonstrate significant inhibitory effects on skin tumor promotion in the in vivo two-stage mouse skin carcinogenesis...
Source: HighBeam Research, Ultraviolet-A triggers signals linked to skin tumor promotion and...