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2004 MAY 6 - (NewsRx.com & NewsRx.net) -- Spontaneous and iatrogenic ovarian hyperstimulation syndrome show differences.
"The recent identification of mutations in the follicle stimulating hormone (FSH) receptor gene, which display an increased sensitivity to hCG and are responsible for the development of spontaneous ovarian hyperstimulation syndrome (OHSS), provides for the first time the molecular basis for the physiopathology of spontaneous OHSS. Based on these recent findings, this paper underlines the differences between spontaneous and iatrogenic OHSS and proposes a model to account for the different chronology between the two forms of the syndrome," scientists writing in the journal Human Reproduction report.
"In the iatrogenic form, the follicular recruitment and enlargement occur during ovarian stimulation with exogenous FSH, while in the spontaneous form, the follicular recruitment occurs later through the stimulation of the FSH receptor by pregnancy-derived hCG," explained A. Delbaere and colleagues, Erasme Hospital, Fertility ...
Source: HighBeam Research, Spontaneous and iatrogenic ovarian hyperstimulation syndrome show...