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Novel tissue-restricted angiogenic factors regulate steroidogenic function.
2004 MAY 6 - (NewsRx.com & NewsRx.net) -- Novel tissue-restricted angiogenic factors regulate steroidogenic function.
"A novel family of angiogenic mitogens have been recently characterized. Endocrine gland-derived vascular endothelial growth factor (EG-VEGF), and the mammalian homologue of Bombina variegata peptide 8 (130), are two highly related endothelial cell mitogens and chemotactic factors with restricted expression profiles and selective endothelial cell activity. These peptides share two cognate G-protein coupled receptors," researchers in the United States report.
"The expression of human EG-VEGF occurs predominantly in steroidogenic glands. Consistent with such an expression pattern, the human EG-VEGF gene promoter has a potential binding site for steroidogenic factor (SF)-1, a pivotal element for steroidogenic-specific transcription. In the human ovary, the expression of EG-VEGF is temporally and spatially complementary to the expression of VEGF-A, both in the follicular and in the luteal phase, suggesting complementary and coordinated roles of these molecules in ovarian angiogenesis," wrote N. Ferrara and colleagues, Genentech Inc., Department of Molecular Oncology.
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- Novel tissue-restricted angiogenic factors regulate steroidogenic function.
- Newspaper article from: Biotech Week May 5, 2004 700+ words
...tissue-selective angiogenic factors raises the possibility...in Biochimica Et Biophysica Acta - Reviews on Cancer...tissue-restricted angiogenic factors. BBA-Rev Cancer...journal Biochimica Et Biophysica Acta - Reviews on Cancer...
- Angiogenic factors increase during distraction osteogenesis.
- Newspaper article from: Angiogenesis Weekly February 13, 2004 700+ words
...com & NewsRx.net) -- Angiogenic factors increase during distraction osteogenesis...the expression of two different angiogenic factors vascular endothelial growth factor...expression for a wide variety of angiogenic factors including angiopoietin 1 and 2...
- Expression of the major angiogenic factors in the placenta of adolescent...
- Magazine article from: Proceedings of the North Dakota Academy of Science Borowicz, Pawel P. Johnson, Mary Lynn Borowczyk, Ewa Vonnahme, Kimberly A. Grazul-Bilska, Anna T. Redmer, Dale A. Reynolds, Lawrence P. April 1, 2005 700+ words
...placental expression of the major angiogenic factors and(or) their receptors in association...placental expression of the major angiogenic factors, gravid uteri were obtained on day...differences in mRNA concentrations for angiogenic factors in PP vs. EA. Reduced expression...
- Angiogenic factors have clinical relevance in patients with lymphoma.
- Newspaper article from: Health & Medicine Week July 26, 2004 700+ words
...com & NewsRx.net) -- Angiogenic factors have clinical relevance in patients...and angiogenin are important angiogenic factors. In 65 patients with non-Hodgkin...Clinical relevance of circulating angiogenic factors in patients with non-Hodgkin...
- Early trials of angiogenic factors have not targeted patients most at risk of...
- Magazine article from: British Medical Journal McKibbin, Martin O'Neill, Damian September 4, 1999 700+ words
...barrier will prevent access of these angiogenic factors to the ocular tissues and the risk...macular degeneration,[2] these angiogenic factors will have ready access to ocular...retinopathy the early clinical trials of angiogenic factors have failed to target those patients...
- Angiogenic factors guide the fabrication of novel biomedical materials.
- Newspaper article from: Medical Devices & Surgical Technology Week July 11, 2004 700+ words
...NewsRx.com & NewsRx.net) -- Angiogenic factors guide the fabrication of novel biomedical materials...endothelial cells by guided stimulation with angiogenic factors. Biosens Bioelectron, 2004;19(11):1401...
- Angiogenic factors mark invasive potential of advanced colorectal malignancy.
- Newspaper article from: Angiogenesis Weekly February 7, 2003 700+ words
...by Sonia Nichols, senior medical writer - Of all the angiogenic factors that have been identified, vascular endothelial growth...related to 5-year patient survival. "Of the several angiogenic factors, VEGF expression at the deepest invasive site of tumor...
- Hypoxia and radiation control angiogenic factors differentially in brain tumors.
- Newspaper article from: Drug Week March 19, 2004 700+ words
...amp; NewsRx.net) -- Hypoxia and radiation control angiogenic factors differentially in brain tumors. "We examined how ionizing...hypoxia inducible factor 1alpha (HIF-1alpha) and the angiogenic factors vascular endothelial growth factor (VEGF) and angiopoietins...
- Presence of angiogenic factors imply chain of events during cerebral ischemia.
- Newspaper article from: Angiogenesis Weekly February 28, 2003 700+ words
...net) -- According to a study from Germany, "the relation between cerebral ischemia and local release of angiogenic factors was investigated after subarachnoid hemorrhage (SAH) in humans." "Time-dependent concentration-changes...
- Anti-angiogenic agents could affect healing after surgery.
- Newspaper article from: Biotech Week April 28, 2004 700+ words
...in Biochimica et Biophysica Acta explain that...release of many angiogenic factors. Regarding the...in Biochimica et Biophysica Acta - Reviews on Cancer...journal Biochimica et Biophysica Acta - Reviews on Cancer...
Source: HighBeam Research, Novel tissue-restricted angiogenic factors regulate steroidogenic...