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Oral contraceptives increase colon cancer risk.

Women's Health Weekly

| May 06, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 MAY 6 - (NewsRx.com & NewsRx.net) -- Oral contraceptives increase colon cancer risk; tubal ligation and abortion decrease risk.

"267,400 female textile workers in Shanghai, who were administered a questionnaire at enrollment into a randomized trial of breast self-examination between October 1989 and October 1991, were followed up until the middle of 2000. Based on the 655 women who developed colon cancer, rate ratios (RRs) were estimated and trends in risk assessed using Cox Proportional Hazards Models," wrote investigators at the University of Illinois.

"Risk was increased in women who used oral contraceptives for over 3 years (RR = 1.56, 95% Confidence Interval (CI) 1.01-2.40). A possible increase in risk was also observed in women who received progestational injections during pregnancy (RR = 1.24, 95% CI 0.95-1.62), but not in relation to the use of injectable contraceptives. A possible reduction in risk was associated with tubal ligation (RR = 0.86, 95% CI 0.71-1.03) and ever having had an induced abortion (RR = 0.84, 95% CI 0.71-1.00)," K.A. Rosenblatt and colleagues reported.

"No trends in risk were observed in relation to ...

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Source: HighBeam Research, Oral contraceptives increase colon cancer risk.

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