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Stromal infiltration may predict tumor invasion in breast FNA biopsy.
2004 MAY 6 - (NewsRx.com & NewsRx.net) -- Stromal infiltration may predict tumor invasion in breast fine-needle aspiration biopsy.
According to a study from the United States, "Clinical management of in situ carcinoma of the breast is different from invasive carcinomas. Thus, it is important to find cytomorphologic criteria to distinguish between these two entities."
"The current study is designed to assess whether, by applying strict cytologic criteria, the status of stromal invasion can be predicted. In this retrospective study, 223 consecutive nonpalpable tumors sampled by ultrasound-guided breast fine-needle aspirates with diagnosis of in situ and invasive carcinoma with histologic follow-up evaluation were retrieved," wrote J. Klijanienko and colleagues, University of Florida, Health Science Center.
"Ten cytologic parameters were evaluated, which included cellular clustering, eosinophilic differentiation, necrosis, tubular structures, dirty background, nuclear anisonucleosis, cellular pleomorphism, cribriform pattern, tubular structures, and stromal infiltration," the researchers wrote.
"Among all the parameters examined, stromal infiltration was the most powerful predictor of status of invasion. Stromal infiltration was significantly higher in invasive ...
- Stromal infiltration may predict tumor invasion in breast FNA biopsy.
- Newspaper article from: Biotech Week May 5, 2004 700+ words
...net) -- Stromal infiltration may predict tumor invasion in breast...demonstrates that stromal infiltration defined by...status of tumor invasion in breast...Cytopathology (Stromal infiltration as a predictor of tumor invasion in breast...
- Insulin-like growth factor-I receptor fosters tumor invasion and metastasis.
- Newspaper article from: Cancer Weekly March 2, 2004 700+ words
...growth factor-I receptor fosters tumor invasion and metastasis. "The breakdown of...receptor (IGF-IR) as a regulator of tumor invasion and the synthesis of MT1-MMP and...IR/IGF axis in the regulation of tumor invasion and metastasis." Zhang and colleagues...
- Stat3 regulates the expression of enzymes that influence tumor invasion.
- Newspaper article from: Biotech Week July 7, 2004 700+ words
...expression of enzymes that influence tumor invasion. According to a study from the United...2 (MMP-2) has been linked with tumor invasion, angiogenesis, and metastasis. However...directly regulates MMP-2 expression, tumor invasion, and metastasis, and that Stat3 activation...
- Brain tumor invasion: clinical patterns of malignant astrocytoma spread....
- Newspaper article from: Cancer Weekly Rosenblum, M. Eisenberg, A. Norman, D. July 20, 1992 700+ words
...in San Diego, California, "Brain tumor invasion is a paramount problem preventing the...were assumed to occur as a result of tumor invasion, and regions shown as high signal...basis for laboratory studies of brain tumor invasion toward the development of new, clinically...
- MMPs degrade certain macromolecules, which may have a role in tumor invasion.
- Newspaper article from: Cancer Weekly April 27, 2004 700+ words
...macromolecules, which may have a role in tumor invasion. According to researchers in Reims...enzymes which play a major role in tumor invasion. They are mainly produced by host...macromolecules which in turn may regulate tumor invasion in some conditions. This ECM degradation...
- The effects of chemokines on tumor invasion are not fully understood.
- Newspaper article from: Angiogenesis Weekly August 6, 2004 700+ words
...amp; NewsRx.net) -- The effects of chemokines on tumor invasion are not fully understood. "Solid tumor and leukemic cells...well studied in vitro, the direct or indirect effects on tumor invasion and metastasis are only poorly evaluated," said researchers...
- Beta-catenin translocalization in nuclei indicate tumor invasion.
- Newspaper article from: Biotech Week August 4, 2004 700+ words
...Beta-catenin translocalization in the nuclei indicate tumor invasion. According to recent research published in the journal...translocalized in the nuclei are closely correlated with tumor invasion." Cheng and associates published their study in Oncology...
- Evodiamine suppresses hepatocyte growth factor-induced tumor invasion.
- Newspaper article from: Biotech Week June 9, 2004 700+ words
2004 JUN 9 - (NewsRx.com & NewsRx.net) -- Evodiamine suppresses hepatocyte growth factor-induced tumor invasion. According to a study from Japan, "tumor cell motility plays a crucial role in the establishment of tumor metastasis...
- Trial tests novel compound targeting tumor invasion and metastasis.
- Newspaper article from: Obesity, Fitness & Wellness Week June 19, 2004 700+ words
2004 JUN 19 - (NewsRx.com & NewsRx.net) -- Wilex AG, Munich, and Fox Chase Cancer Center, Philadelphia, announced the start of a clinical trial with a novel compound, WX-UK1, targeting tumor cell invasion and metastasis. This Phase I trial marks the start of an innovative collaboration between
- Microbial keratitis.(bacterial infection of the cornea)
- Magazine article from: Review of Optometry January 15, 2006 700+ words
...with fluorescein. (3) Diffuse epithelial edema and stromal infiltration may be seen surrounding the ulceration. Mucopurulent...The depth and location of the epithelial defect and stromal infiltration should be documented; the anterior chamber reaction...
Source: HighBeam Research, Stromal infiltration may predict tumor invasion in breast FNA biopsy.