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2004 MAY 6 - (NewsRx.com & NewsRx.net) -- Zonagen, Inc., (ZONA) announced that data generated at Zonagen in collaboration with scientists at the University of Illinois-Chicago that indicate the potential for Progenta for the treatment of breast cancer were presented at the 2004 Annual Meeting of the American Association for Cancer Research in Orlando, Florida.
Dr. Ronald Wiehle, the company's director of research and development, presented the data. The poster presentation elaborated upon the company's recent finding that Progenta shows significant activity against hormone-dependent breast cancer induced in rats by DMBA.
DMBA is a tumor-inducing agent used in a well-accepted breast cancer tumor model. In the study, rats were given DMBA at 50 days of age and entered randomly into treatment groups when the lead tumor reached 12 mm in size.
Groups of 10 to 13 rats were treated for 28 days with vehicle (oil) or with varying doses of Progenta with or without progesterone. Progenta reduced the size of established tumors significantly and prevented the appearance of new ...
Source: HighBeam Research, Progenta breast cancer treatment data presented at cancer research...