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Locoregional recurrence is lower in recent years after breast-conserving surgery.

Women's Health Weekly

| May 06, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 MAY 6 - (NewsRx.com & NewsRx.net) -- Improved patient selection may be partly responsible for lower rates of recurrence after breast-conserving surgery, researchers say.

"The aim of our study was to compare the locoregional recurrence (LRR) rates after breast conserving surgery and mastectomy between the time periods of 1985-1992 and 1993-1999. The first period reflects the early experiences with breast conservation," investigators in Netherlands report.

"The second period covers the years when a mammographical screening program was introduced for women 50-69 years of age. We collected data on 1212 patients with 1264 resectable breast cancers (i.e., stage I, IIA, IIB and IIIA), of which 385 were removed by breast conserving surgery and 879 by mastectomy. During follow-up, 47 locoregional recurrences developed after breast conservation, and 67 after mastectomy," wrote M.F. Ernst and colleagues, St. Elizabeth Hospital, Department of Surgery.

"The 5- and 10-year locoregional recurrence rates were 5.7% (95% Confidence Interval (CI) 4.0-7.4) and 11.0% (95% CI 8.0-14.0), respectively, after mastectomy and 7.3% (95% CI 4.5-10.1) and 15.8% (95% CI 11.2-20.4), respectively, after breast conservation. The 8-year locoregional recurrence rate after breast conservation decreased from ...

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