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Frozen section and permanent analysis of sentinel nodes are equivalent.

Women's Health Weekly

| May 06, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 MAY 6 - (NewsRx.com & NewsRx.net) -- Using frozen section (FS) or permanent section (PS) analysis of sentinel node biopsies in breast cancer does not affect patient quality of life, researchers report.

According to published research from the United States, "In the absence of data from randomized trials, a formal decision analysis was undertaken to quantify the relative value of the patients quality of life with regard to performing intraoperative frozen section (FS) versus permanent section (PS) analysis of the sentinel lymph node (SLN) for breast cancer."

"Assumptions for this analysis were based on data from 203 nodal basins where the prevalence of nodal metastasis was 26.1%; the FS sensitivity was 68% and FS false-positive rate was 0.7%. DATA 4.0 was used to model the decision analysis," wrote C. Chao and colleagues, University of Texas, Medical Branch.

"The two branches of the tree represent the two surgical options of either FS analysis intraoperatively, accompanied by immediate axillary dissection for positive nodes, versus PS analysis followed by reoperative axillary dissection. The expected utility (EU) with the FS strategy is ...

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Source: HighBeam Research, Frozen section and permanent analysis of sentinel nodes are...

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