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Typhoid fever vaccines cause adverse events.

Vaccine Weekly

| May 05, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 MAY 5 - (NewsRx.com & NewsRx.net) -- Typhoid fever vaccines cause adverse events.

According to a study from the United States, "Vaccines against Salmonella enterica serotype Typhi are used for prophylaxis of international travelers and have potential use as counter-bioterrorism agents. The Vaccine Adverse Event Reporting System (VAERS) cannot usually establish causal relationships between vaccines and reported adverse events without further research, but has successfully detected unrecognized side effects of vaccine. We reviewed reports to VAERS for U.S.-licensed typhoid fever vaccines for the period of July 1990 through June 2002.

"We received 321 reports for parenteral Vi capsular polysaccharide vaccine and 345 reports for live, oral, attenuated Ty21a vaccine, with 7.5% and 5.5%, respectively, describing death, hospitalization, permanent disability, or life-threatening illness," reported Elizabeth M. Begier at the U.S. Food and Drug Administration and fellow members of the Vaccine Adverse Event Reporting System Working Group. "Unexpected frequently reported symptoms included dizziness and pruritus for Vi vaccine and fatigue and myalgia for Ty21a vaccine."

The researchers reported, "Gastroenteritis-like illness after receipt of Ty21a vaccine and abdominal pain after ...

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Source: HighBeam Research, Typhoid fever vaccines cause adverse events.

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