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HIV-positive U.S. military personnel accidentally vaccinated against smallpox.
2004 MAY 5 - (NewsRx.com & NewsRx.net) -- Ten U.S. military personnel were discovered to be HIV-positive after being vaccinated against smallpox, but did not experience any harmful effects from the vaccination, according to a new study.
In people with weakened immune systems, there is a chance that the live virus in the smallpox vaccine, rather than immunizing them, can result in an infection that gets progressively worse. People who are known to be HIV-positive would not typically be given a smallpox vaccination because of this potentially fatal risk.
More than 438,000 U.S. soldiers were vaccinated against smallpox between December 2002 and October 2003. Of the 10 later identified as HIV-positive, only 3 were known to be "primary" vaccine recipients, or had never been vaccinated before, according to the in the May 1, 2004, issue of Clinical Infectious Diseases.
Those who had previously received smallpox vaccinations may have benefited from some "leftover" immunity, but the fact that none of the soldiers had full-blown AIDS at the time of vaccination was probably a key factor in preventing a dangerous reaction.
"Fundamentally, it is because their immune systems were not yet impaired or diminished or compromised, because they were presumably early in ...
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Source: HighBeam Research, HIV-positive U.S. military personnel accidentally vaccinated against...