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Technological advances and genomics in metazoan parasites reviewed.

Vaccine Weekly

| May 05, 2004 | COPYRIGHT 2004 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2004 MAY 5 - (NewsRx.com & NewsRx.net) -- A scientist reviews technological advances and genomics in metazoan parasites in a recent issue of the International Journal for Parasitology.

According to recent research from Scotland, "Molecular biology has provided the means to identify parasite proteins, to define their function, patterns of expression, and the means to produce them in quantity for subsequent functional analyses. Whole genome and expressed sequence tag programs, and the parallel development of powerful bioinformatics tools, allow the execution of genome-wide between stage or species comparisons and meaningful gene-expression profiling. The latter can be undertaken with several new technologies such as DNA microarray and serial analysis of gene expression.

"Proteome analysis has come to the fore in recent years providing a crucial link between the gene and its protein product," said David P. Knox at the Moredun Research Institute in Midlothian. "RNA interference and ballistic gene transfer are exciting ...

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