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Genetic factors regulate 3'-azido-3'-deoxythymidine-induced cytogenetic damage.
2004 MAY 5 - (NewsRx.com & NewsRx.net) -- Genetic factors regulate 3'-azido-3'-deoxythymidine-induced cytogenetic damage.
"The activation of telomerase in phytohemagglutinin-stimulated peripheral lymphocytes is thought to play a role in telomere maintenance and DNA repair. Considering the importance of this enzyme in both cancer and senescence" the "telomerase inhibitor 3'-azido-3'-deoxythymidine was studied for its effect "on the frequency of chromosomal aberrations and micronuclei induced in peripheral blood lymphocytes (PBL) of elderly monozygotic and dizygotic twins, evaluated with respect to the genotoxic effects induced in unrelated young subjects," wrote scientists in Italy.
Results "show that the cytogenetic damage induced by 3'-azido-3'-deoxythymidine in human PBL was mainly regulated by genetic factors and allowed the identification of hypersensitive subjects," D. Caporossi and colleagues report.
"Ageing, which did not modify the individual susceptibility to 3'-azido-3'-deoxythymidine induction of chromosome ...
- Favorable Genetic Factors Same For Progression, Vaccine Efficacy.(Brief Article)
- Newspaper article from: Vaccine Weekly October 3, 2001 700+ words
...found that people with HLA class I genetic factors associated with slower disease...doses This article was prepared by Vaccine Weekly editors from staff and other reports. Copyright 2001, Vaccine Weekly via NewsRx.com & NewsRx...
- For Adolescent Crime Victims, Genetic Factors Play Lead Role.
- Newspaper article from: Biotech Week June 24, 2009 700+ words
...peers, I had reasons to suspect that genetic factors could influence the odds of someone...The data convinced Beaver that genetic factors explained a surprisingly significant...victimized repeatedly, the effect of genetic factors accounted for a whopping 64 percent...
- Advances in the field of schizophrenia research: New genetic factors identified.
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...affect. Environmental as well as genetic factors form a complex interplay that leads...extraordinarily difficult search for relevant genetic factors. The studies were carried out by...hereditary pattern of the underlying genetic factors, however, proved extraordinarily...
- Genetic factors that determine breast density may determine breast cancer risk.
- Newspaper article from: Cancer Weekly May 27, 2003 700+ words
...NewsRx.com & NewsRx.net) -- Genetic factors that determine breast density may...report. "We reasoned that if the genetic factors that underlie breast density increase...researchers concluded: "Thus, the genetic factors that determine breast density may...
- Overlapping genetic factors in pathological gambling and major depression.
- Press release article from: M2 Presswire September 22, 2005 700+ words
...2005-YALE UNIVERSITY: Overlapping genetic factors in pathological gambling and major...heavily influenced by overlapping genetic factors, according to a study by researchers...depression that is attributable largely to genetic factors," Potenza said. "This study highlights...
- HSV Viral Genetic Factors Regulate Number of Genome Copies in Latently Infected...
- Newspaper article from: Blood Weekly September 7, 1998 700+ words
...simplex virus (HSV) in vivo. Viral genetic factors that determine in vivo reactivation...observation is to distinguish between viral genetic factors that regulate the establishment of...infected neurons is regulated by viral genetic factors, the authors said. This research...
- Searching for Protective Genetic Factors Against AD.
- Newspaper article from: Gene Therapy Weekly Rodriguez, Rod May 10, 1999 700+ words
...suggests that those searching for genetic factors conferring a lifelong reduced liability...et al. explored the concept that genetic factors might be found which reduce the likelihood...span. "The results suggest that genetic factors conferring a lifelong reduced liability...
- Interleukin Genetics Announces Presentation on Genetic Factors for Osteoporosis...
- Press release article from: Business Wire October 20, 1999 700+ words
...reporting the association of their genetic factors with a significantly increased risk...on the relation between different genetic factors in the IL-1 gene cluster and their...diagnostic tests and therapeutics based on genetic factors that regulate control points in the...
