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P73 A4T14 genotype associated with cervical cancer risk.
2004 MAY 5 - (NewsRx.com & NewsRx.net) -- P73 A4T14 genotype is associated with risk of cervical cancer.
A "possible association between cervical cancer and p73 G4C14-to-A4T14 in exon 2 and p53 Arg72Pro polymorphisms" was examined in an incident case-control study comprised of 112 cervical cancer patients, 320 healthy female controls and 122 non-cancer female outpatient controls," wrote investigators in Japan.
"Risk estimation for each genotype by an unconditional logistic model demonstrated a possible association between the p73 A4T14 variant and the risk of cervical cancer in" a "Japanese population (OR = 1.57; 95%CI, 0.99-2.48, P = 0.053)," reported Y. Niwa and colleagues.
"There was no significant difference in the p53 Arg72Pro genotype frequency between the controls and cases," researchers concluded.
Niwa and colleagues ...
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Source: HighBeam Research, P73 A4T14 genotype associated with cervical cancer risk.