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HIV synthetic peptide-cocktail prevents SHIV transmission.
2004 MAY 5 - (NewsRx.com & NewsRx.net) -- An HIV synthetic peptide-cocktail prevented SHIV transmission in rhesus macaques.
"An effective vaccine against human immunodeficiency virus (HIV) should not only protect from infection and development of acquired immunodeficiency syndrome (AIDS), but also prevent potential transmission to naive partners. We recently reported protection of rhesus macaques from chronic simian-human immunodeficiency virus (SHIV) infection and AIDS by an HIV envelope peptide-cocktail vaccine. In the present case study, we observed that one of the vaccinated females, with undetectable circulating virus, when housed in a pair with a naive male, did not transmit the infection over a 35-week period of social contact," investigators in the United States report.
"Subsequent experimental challenge of the male with the same SHIV strain resulted in high-level infection and transmission to its female cage-mate," said Lori R. Hill and colleagues at the University of Texas M.D. Anderson Cancer Center. "However, the virus was undetectable in the female by 12 weeks without further vaccination, validating the multivalent peptide ...
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Source: HighBeam Research, HIV synthetic peptide-cocktail prevents SHIV transmission.