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AIDS virus is vulnerable in initial stage of infection.
2004 APR 21 - (NewsRx.com & NewsRx.net) -- In individuals newly infected with HIV, the virus that establishes infection is susceptible to inactivation by antibodies from the transmitting partner, according to a recent study by researchers at the University of Alabama at Birmingham (UAB).
Details of the study were published in Science.
The new information may be helpful in developing a vaccine against HIV. "Following infection, it takes a couple of weeks for the body's immune system to mount an attack, allowing the virus to replicate unchecked," said Cynthia Derdeyn, PhD, research instructor with the department of microbiology at UAB and lead investigator of the study. "However, our study shows that during this time the virus also is especially vulnerable. Perhaps this period of greater susceptibility can be exploited."
Heterosexual transmission accounts for the majority of HIV infections worldwide. But studies aimed at determining how the virus is acquired have focused primarily on homosexual and mother-to-infant transmissions. "In this study, we closely examined male-to-female and female-to-male transmissions," Derdeyn said.
The study was part of a larger ongoing project in Zambia led by Dr. Susan Allen, associate professor of public health at UAB, to test, counsel and monitor heterosexual couples in which one partner is HIV-positive. "All couples are encouraged to use condoms and to take precautions to ...
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Source: HighBeam Research, AIDS virus is vulnerable in initial stage of infection.