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AIDS vaccine to be tested on humans.
2004 APR 14 - (NewsRx.com & NewsRx.net) -- Researchers for the University of Massachusetts (UMass) Medical School said they will begin human testing of an AIDS vaccine which attacks aggressively the virus that causes the disease.
The human immunodeficiency virus, or HIV, which causes AIDS, constantly changes its outer coating to dodge the immune system. The UMass vaccine attempts to target five strains of HIV simultaneously, a process that worked on animals according to the researchers.
"We underestimate the complexity of HIV," said Shan Lu, MD, a UMass scientist chiefly responsible for the vaccine's development. "If you don't even understand your enemy and yet you think you can defeat your enemy, that's naive."
The UMass trial is one of at least 18 new approaches to AIDS vaccines underwritten by the U.S. National Institutes of Health (NIH), and one of four human trials with $70 million in NIH funding.
Vaccine research is still waiting for the breakthrough that AZT had, when that first effective AIDS medicine boosted treatment in the mid-1980s, said Margaret Johnston, the director of the vaccine and prevention research program in the NIH's AIDS division.
World health officials estimate that 42 million people are infected with HIV and 3 million died of AIDS last year. In many poor areas where AIDS has spread, vaccination is the best way to prevent future infections.
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Source: HighBeam Research, AIDS vaccine to be tested on humans.