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Vaccination for neurotropic disease recommended in children with brain tumors.
2004 APR 7 - (NewsRx.com & NewsRx.net) -- Researchers recommend immunization against vaccine-preventable potentially neurotropic diseases in children treated for malignant brain tumors with HIT-91 chemo- and radiotherapy.
According to published research from Austria, "Following surgery, chemotherapy and/or irradiation, patients with malignant brain tumors are at risk of neurotropic diseases, although these are partly vaccine-preventable. In a retrospective, controlled, observational study, the impact of the German-Austrian chemo- and radiotherapy protocol (HIT-91) on antibody concentrations against vaccine-preventable diseases and on vaccination behavior was analyzed. A significant level of seronegativity for measles- and mumps-IgG, and a reduced protection induced by inactivated vaccines was observed after HIT-91 therapy."
"Failure of seroconversion following measles and mumps live vaccinations was assessed in the HIT-91-treated group and in a group with benign brain tumors (BBT)," said E. Schuller and colleagues at the University of Vienna. "Analysis of cellular immunological parameters revealed significant aberrations in the HIT-91-treated group 36 months after completion of HIT-91 therapy. A retrospective analysis of the ...
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Source: HighBeam Research, Vaccination for neurotropic disease recommended in children with...